The role of nutritional factors in fat-free mass preservation and body composition changes after bariatric surgery: a systematic review of the available evidence

Eat Weight Disord. 2025 Jul 6;30(1):51. doi: 10.1007/s40519-025-01761-0.ABSTRACTBACKGROUND: Bariatric surgery (BS) is an effective treatment for obesity, but it often leads to significant changes in body composition, including loss of fat-free mass (FFM). Nutritional intake plays a crucial role in i

Association between weight loss and reproductive outcomes among women with overweight or obesity: a cohort study using UK real-world data

Hum Reprod. 2025 Jul 6:deaf122. doi: 10.1093/humrep/deaf122. Online ahead of print.ABSTRACTSTUDY QUESTION: In women with BMI ≥25 kg/m2, does a 10-25% weight loss versus stable weight increase the chance of pregnancy?SUMMARY ANSWER: In women with overweight or obesity, weight loss was associated with

Comparison and prognostic analysis of focal segmental glomerulosclerosis patients with or without nephrotic syndrome at onset

BMC Nephrol. 2025 Jul 5;26(1):353. doi: 10.1186/s12882-025-04292-z.ABSTRACTBACKGROUND: Focal segmental glomerulosclerosis (FSGS) constituted one of the most common causes of end-stage kidney disease. We aimed to compare the presentation and prognosis for FSGS patients based on whether they met the c

Variations in the clinical practice of blood pressure and sedo-analgesia management for intracerebral hemorrhage: a case-based survey of Chinese healthcare workers

BMC Neurol. 2025 Jul 5;25(1):279. doi: 10.1186/s12883-025-04301-6.ABSTRACTBACKGROUND: Blood pressure (BP) management during the acute phase of intracerebral hemorrhage (ICH) is critical to improving patient prognosis. Besides routine antihypertensive medications, sedo-analgesia (i.e., a combination

Postpartum diuretic administration and hospital readmission: a systematic review and meta-analysis

Am J Obstet Gynecol MFM. 2025 Jul 2:101738. doi: 10.1016/j.ajogmf.2025.101738. Online ahead of print.ABSTRACTOBJECTIVE: We aimed to determine if postpartum administration of loop diuretic therapy among patients at risk of or diagnosed with a hypertensive disorder of pregnancy impacts the rate of hos

Effect of diabetes mellitus on spinal cord high signal relief after anterior cervical spine surgery in patients with cervical spondylotic myelopathy

BMC Surg. 2025 Jul 3;25(1):268. doi: 10.1186/s12893-025-03025-1.ABSTRACTBACKGROUND: In patients with cervical spondylotic myelopathy (CSM), the presence of a high spinal cord signal (HCS) on T2-weighted magnetic resonance imaging (MRI) is a critical diagnostic marker. Diabetes mellitus (DM), a commo

Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis

Lancet Diabetes Endocrinol. 2025 Jun 30:S2213-8587(25)00068-3. doi: 10.1016/S2213-8587(25)00068-3. Online ahead of print.ABSTRACTBACKGROUND: Pregnancy is a state of increased metabolic demand that necessitates major changes in endocrine physiology. Gestational thyroid dysfunction and gestational dia

Effect of positive airway pressure treatment on pulmonary artery pressure in obstructive sleep apnoea and/or obesity hypoventilation syndrome with pulmonary hypertension: a systematic review and meta-analysis

Intern Med J. 2025 Jul 2. doi: 10.1111/imj.70137. Online ahead of print.ABSTRACTBACKGROUND: Patients with obstructive sleep apnoea (OSA) and/or obesity hypoventilation syndrome (OHS) are at increased risk of developing pulmonary hypertension (PH). The presence of PH is associated with a worse progno

Neonatal outcome in late preterm twin gestation: impact of antenatal corticosteroids therapy before 34 weeks

BMC Pregnancy Childbirth. 2025 Jul 2;25(1):679. doi: 10.1186/s12884-025-07533-z.ABSTRACTBACKGROUND: The effects of antenatal corticosteroid (ACS) exposure before 34 weeks on neonates born in the late preterm period are a subject of controversy. We aimed to investigate the impact of ACS exposure befo

Perioperative recognition and management of rare irrigation-related complications in unilateral biportal endoscopy under general anesthesia: two case reports

Eur Spine J. 2025 Jul 3. doi: 10.1007/s00586-025-09077-4. Online ahead of print.ABSTRACTBACKGROUND: Unilateral biportal endoscopy (UBE) is a widely used minimally invasive technique for treating lumbar disc herniation, employing continuous fluid infusion to maintain a clear surgical field. However,

Primary hypertension in German children and adolescents: Low treatment rates and dominance of ACE inhibitors in an analysis of 7,482 cases for the period 2005 to 2023

Int J Clin Pharmacol Ther. 2025 Jul 2. doi: 10.5414/CP204857. Online ahead of print.ABSTRACTAIMS: To investigate prescription patterns in children and adolescents receiving treatment for primary hypertension.MATERIALS AND METHODS: Cumulative prescriptions within the 12-month period before the index

Efficacy and safety of anti-PD-1 antibodies plus small molecule anti-angiogenic drugs and chemotherapy in gastric cancer peritoneal metastasis: a multicenter real-world study

BMC Cancer. 2025 Jul 1;25(1):1028. doi: 10.1186/s12885-025-14426-z.ABSTRACTBACKGROUND: Immunotherapy combined with chemotherapy has emerged as the first-line standard treatment for advanced gastric cancer. However, obvious survival benefits in patients with peritoneal metastatic gastric cancer remai

Spontaneous renal artery thrombosis causing circulatory insufficiency in a newborn- a case report

BMC Pediatr. 2025 Jul 2;25(1):490. doi: 10.1186/s12887-025-05809-z.ABSTRACTBACKGROUND: Renal artery thrombosis in newborns is a severe condition with high morbidity and mortality. Although neonates harbor intrinsic and external risk factors for thrombotic events of the renal vasculature, their occur

Combining endoscopic variceal ligation and omeprazole sodium in treating upper gastrointestinal hemorrhage combined with liver cirrhosis

BMC Gastroenterol. 2025 Jul 1;25(1):446. doi: 10.1186/s12876-025-04037-0.ABSTRACTBACKGROUND: Cirrhosis, a common chronic liver disease, leads to portal hypertension and complications like ascites and variceal bleeding. Endoscopic variceal ligation (EVL) is the preferred treatment for variceal bleedi

Genetic association analysis between LDL-c lowering drugs and portal hypertension using Mendelian randomization analysis

Sci Rep. 2025 Jul 1;15(1):22238. doi: 10.1038/s41598-025-08153-5.ABSTRACTClinical guidelines recommend the use of statins to reduce portal pressure and alleviate portal hypertension (PH). However, there is a lack of population-level studies on the use of non-statin Low-Density Lipoprotein Cholestero

Machine learning and transformer models for prediction of postoperative pneumonia risk in patients with lower limb fractures

Sci Rep. 2025 Jul 1;15(1):22409. doi: 10.1038/s41598-025-04623-y.ABSTRACTPostoperative pneumonia, a prevalent complication arising from lower limb fracture surgery, can significantly prolong hospitalization periods and elevate mortality rates. Consequently, early prevention and identification of thi

Clinical characteristics and prognosis of adult orbital cellulitis in a tertiary general hospital

Sci Rep. 2025 Jul 1;15(1):20585. doi: 10.1038/s41598-025-06382-2.ABSTRACTAdult orbital cellulitis (OC) is a rare ophthalmic condition. This study aimed to identify risk factors influencing the prognosis of adult OC by evaluating the clinical characteristics and prognosis in an Asian population in so

Cyclodextrin attenuates atherosclerosis by diminishing gasdermin D (GSDMD)-mediated pyroptosis

Sci Rep. 2025 Jul 1;15(1):21605. doi: 10.1038/s41598-025-04889-2.ABSTRACTPyroptosis, a programmed form of cell death, typically increases during the atherosclerosis development. Cyclodextrins are oligosaccharides with anti-atherosclerotic properties. Therefore, the present study aims to explore the

Integrative in Silico and in vitro validation suggest LINC00963 and SNHG15 as candidate biomarkers for coronary artery disease

Sci Rep. 2025 Jul 1;15(1):21501. doi: 10.1038/s41598-025-08777-7.ABSTRACTDespite notable advancements in prevention, medication, and treatment approaches, coronary artery disease (CAD) remains a significant challenge for healthcare systems and the economy. In relation to CAD, long non-coding RNAs (l

Satisfaction with life in young adults with type 1 diabetes mellitus

Sci Rep. 2025 Jul 1;15(1):20777. doi: 10.1038/s41598-025-07675-2.ABSTRACTThe rules for therapy and self-monitoring in type 1 diabetes mellitus (T1DM) can significantly affect the satisfaction and quality of life of young people. This study assesses the level of life satisfaction in young adults with

Transcatheter Versus Surgical Approach for the Treatment of Aortic Stenosis in Patients With Concomitant Coronary Artery Disease: A Systematic Review and Meta-Analysis

Catheter Cardiovasc Interv. 2025 Jul 1. doi: 10.1002/ccd.31697. Online ahead of print.ABSTRACTAortic stenosis (AS) with concomitant coronary artery disease (CAD) requires an approach that addresses both valvular and coronary pathology. While surgical aortic valve replacement (SAVR) with coronary art

Unveiling Cardiovascular Risk Among Older Adults in Eastern India: A Community-Based Cross-Sectional Study

Cureus. 2025 May 29;17(5):e85063. doi: 10.7759/cureus.85063. eCollection 2025 May.ABSTRACTBackground Cardiovascular disease (CVD) poses major public health challenges in low-resource settings like India, where it contributes significantly to premature mortality and morbidity. This study assessed 10-

AI-based identification of patients who benefit from revascularization: a multicenter study

medRxiv [Preprint]. 2025 Jun 12:2025.06.11.25329295. doi: 10.1101/2025.06.11.25329295.ABSTRACTBACKGROUND AND AIMS: Revascularization in stable coronary artery disease often relies on ischemia severity, but we introduce an AI-driven approach that uses clinical and imaging data to estimate individuali

The association between childhood obesity and major adverse liver outcomes in adolescence and young adulthood

JHEP Rep. 2025 Apr 11;7(7):101425. doi: 10.1016/j.jhepr.2025.101425. eCollection 2025 Jul.ABSTRACTBACKGROUND & AIMS: Paediatric obesity is associated with liver steatosis and injury. We aimed to investigate the association between paediatric obesity and the risk of major adverse liver outcomes (MALO