Hypertension is associated with better brain health outcomes in older-age asymptomatic carotid disease populations - A Multi-Cohort Study

Res Sq [Preprint]. 2026 Sep 10:rs.3.rs-10731777. doi: 10.21203/rs.3.rs-10731777/v1.ABSTRACTBACKGROUND: Blood pressure (BP) management is highly relevant for cardiovascular and brain health outcomes. Although clinical guidelines are trending towards increasingly strict BP control, some discordant res

Adrenocortical Carcinoma with Suspected Dual Cortisol and Aldosterone Secretion: A Case Report

J ASEAN Fed Endocr Soc. 2026 Aug;41(2):124-130. doi: 10.15605/jafes.041.02.5875. Epub 2026 Aug 7.ABSTRACTAdrenocortical carcinoma (ACC) is a rare malignancy, accounting for 0.05-2% of all malignant tumors. Most cases are sporadic and asymptomatic, often discovered incidentally via imaging. However,

Emerging Therapeutics in Hypertension: Evidence, Clinical Readiness, and Implementation

Curr Probl Cardiol. 2026 Sep 29:103470. doi: 10.1016/j.cpcardiol.2026.103470. Online ahead of print.ABSTRACTHypertension remains the leading modifiable contributor to cardiovascular disease worldwide, yet diagnosis, sustained treatment, and blood pressure (BP) control remain inadequate. This narrati

The natural history of untreated small (

Neurosurg Rev. 2026 Sep 29;49(1):590. doi: 10.1007/s10143-026-04507-3.ABSTRACTThe clinical management of small, unruptured intracranial aneurysms, particularly those measuring less than 5 mm, represents a significant area of debate in neurovascular surgery. The decision to pursue invasive treatment

Cancer and Hypertension: Shared Mechanisms, Treatment Interactions, and Clinical Management

Cancer Med. 2026 Oct;15(10):e72319. doi: 10.1002/cam4.72319.ABSTRACTCancer and hypertension (HTN) frequently coexist, and their relationship is increasingly recognized as a clinically relevant intersection between oncology and cardiovascular medicine. However, the extent to which this association re

Pancreatic arteriovenous malformations as a manifestation of hereditary haemorrhagic telangiectasia (Rendu-Osler-Weber disease): a systematic review

BMJ Open Gastroenterol. 2026 Sep 25;13(1):e002491. doi: 10.1136/bmjgast-2026-002491.ABSTRACTOBJECTIVES: Limited data are available on pancreatic arteriovenous malformations (AVMs) in patients with hereditary haemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber disease. This systematic

Fixed-dose combination versus multi-pill combination antihypertensive therapy in medication-defined apparent treatment-resistant hypertension: real-world evidence on healthcare utilization and health-related quality of life

Front Pharmacol. 2026 Sep 11;17:1903129. doi: 10.3389/fphar.2026.1903129. eCollection 2026.ABSTRACTBACKGROUND: Fixed-dose combination (FDC) antihypertensive therapy is recommended by hypertension guidelines to improve adherence and blood pressure control. However, its association with healthcare uti

Mapping Pharmacogenomic Determinants of Adverse Drug Reactions in Hypertension: A Systematic Review

Pharmaceuticals (Basel). 2026 Sep 18;19(9):1488. doi: 10.3390/ph19091488.ABSTRACTObjectives: Adverse drug reactions (ADRs) to antihypertensive medications contribute to poor medication adherence and treatment discontinuation. Pharmacogenomic approaches offer a potential means of identifying genetic

Arterial occlusive events in CML patients on TKIs: a real-world study including a large proportion of older patients

Int J Hematol. 2026 Sep 25. doi: 10.1007/s12185-026-04284-1. Online ahead of print.ABSTRACTThe prognosis of chronic myeloid leukemia (CML) has greatly improved with the introduction of tyrosine kinase inhibitors (TKIs), but the high incidence of cardiovascular events, including arterial occlusive ev

Magnesium sulfate for severe preeclampsia and eclampsia management at the primary healthcare level in sub-Saharan Africa: a systematic review

Front Reprod Health. 2026 Sep 10;8:1911083. doi: 10.3389/frph.2026.1911083. eCollection 2026.ABSTRACTBACKGROUND: Preeclampsia and eclampsia are major causes of maternal and perinatal morbidity and mortality in low- and middle-income countries. Magnesium sulfate (MgSO₄) is the most effective interven

Dosing of anti-infective drugs in patients undergoing therapeutic plasma exchange - considerations for practical application: a narrative review

Crit Care. 2026 Sep 24;30(1):493. doi: 10.1186/s13054-026-06306-0.ABSTRACTBACKGROUND: Therapeutic plasma exchange (TPE) is used in a wide range of indications and patient populations. The current guidelines of the American Society for Apheresis on the use of therapeutic apheresis in clinical practic

Utility of Routine Testing in Asymptomatic Markedly Elevated Blood Pressure in the Emergency Department: A Prospective Cohort Study

J Emerg Med. 2026 Sep 1;90:65-75. doi: 10.1016/j.jemermed.2026.08.018. Online ahead of print.ABSTRACTBACKGROUND: Routine diagnostic testing for asymptomatic adults with markedly elevated blood pressure (BP) in the emergency department (ED) imposes a substantial operational burden despite uncertain c

Catheter-Based Renal Denervation in Uncontrolled and Resistant Hypertension: Evidence, Guidelines, Special Populations and Clinical Implementation

J Cardiovasc Dev Dis. 2026 Sep 7;13(9):443. doi: 10.3390/jcdd13090443.ABSTRACTHypertension remains the leading modifiable cause of cardiovascular death, yet fewer than one in four treated adults achieves guideline-recommended blood pressure targets. Catheter-based renal denervation interrupts effere

Ignatzschineria indica bacteremia in a fatal case of accidental wound myiasis

Folia Microbiol (Praha). 2026 Sep 24. doi: 10.1007/s12223-026-01588-x. Online ahead of print.ABSTRACTIgnatzschineria indica is a rare Gram-negative bacterium increasingly recognized as a potential human pathogen associated with wound myiasis and severe bloodstream infections. Here we report a fatal

Preserved Ejection Fraction Despite Progressive Functional Decline in a Patient With Single-Ventricle Physiology Without Documented Successful Surgical Palliation

Cureus. 2026 Aug 24;18(8):e115087. doi: 10.7759/cureus.115087. eCollection 2026 Aug.ABSTRACTSeventh-decade survival with single-ventricle congenital heart disease (CHD) without documented successful surgical palliation is exceedingly rare. The prognostic value of ejection fraction (EF) in this popul

Nurse-led interventions for hypertension management in Sub-Saharan Africa: A scoping review

Int J Nurs Stud Adv. 2026 Aug 11;11:100656. doi: 10.1016/j.ijnsa.2026.100656. eCollection 2026 Dec.ABSTRACTBACKGROUND: Sub-Saharan Africa exhibits the lowest global rates of hypertension detection, treatment, and control. Task shifting from traditionally physician-led care to other healthcare team m

Targeting pulmonary and arterial chemoreceptors via inhaled therapeutics: A novel pathway to blunt hypoxia-induced pulmonary hypertension?

Pulm Pharmacol Ther. 2026 Sep 23;95:102450. doi: 10.1016/j.pupt.2026.102450. Online ahead of print.ABSTRACTBACKGROUND: Group-3 hypoxia-induced pulmonary hypertension (HPH) associated with obstructive sleep apnea (OSA) and high-altitude exposure is characterized by a maladaptive chemoreflex phenotype

Prescribers' adherence to clinical practice guidelines for the management of hypertension at public hospitals in Northwest Ethiopia: An explanatory sequential mixed-methods study

Sage Open Chronic Dis. 2026 Mar 19;17:27558428261420524. doi: 10.1177/27558428261420524. eCollection 2026 Jan-Dec.ABSTRACTBACKGROUND: Hypertension (HTN) is a leading lifestyle disease and a major cause of morbidity and mortality worldwide, especially in sub-Saharan Africa. Clinical practice guidelin

Oral antihypertensive agents in hypertensive pregnancies and adverse maternal and perinatal outcomes: study protocol for a target trial emulation using Dutch electronic health record data

BMJ Open. 2026 Sep 22;16(9):e121623. doi: 10.1136/bmjopen-2026-121623.ABSTRACTINTRODUCTION: Hypertensive disorders of pregnancy (HDP) are associated with maternal and neonatal morbidity. Although delivery is the definitive treatment, antihypertensive agents are often prescribed to control blood pres

Beta-blockers in cardiovascular medicine - current status - Where are there still "strong" indications for beta-blockers?

Dtsch Med Wochenschr. 2026 Sep;151(19):1080-1085. doi: 10.1055/a-2912-5554. Epub 2026 Sep 21.ABSTRACTThis article presents recommendations for the use of beta-blockers (BB) according to current guidelines and the underlying evidence. Until the last decade, BBs were recommended as first-line therapie

Treatment-resistant hypertension in the primary care setting

J Osteopath Med. 2026 Sep 22. doi: 10.1515/jom-2026-0011. Online ahead of print.ABSTRACTCONTEXT: Rates of treatment-resistant hypertension in the United States are increasing despite our better understanding of underlying mechanisms, lifestyle and pharmacologic approaches, and with refinement of tre

ATS Core Curriculum 2026 Adult Pulmonary Medicine: Pulmonary Hypertension Diagnosis and Management

ATS Sch. 2026 Sep 21:aapag062. doi: 10.1093/atsscholar/aapag062. Online ahead of print.ABSTRACTThe American Thoracic Society Core Curriculum provides an update in adult and pediatric pulmonary disease, medical critical care, and sleep medicine at the annual International Conference. The 2026 Adult P

Systematic review and network meta-analysis for the 2026 update of the evidence-based clinical practice guidelines for the management with immunosuppressive therapies and biologic agents of membranous nephropathy

Clin Exp Nephrol. 2026 Sep 19. doi: 10.1007/s10157-026-02944-4. Online ahead of print.ABSTRACTBACKGROUND: Multiple immunosuppressive therapies are used to induce remission in membranous nephropathy, but differences in study populations, treatment regimens, and outcome definitions complicate comparis

Out-of-pocket expenditure on medicine for chronic patients and its economic impact on Indian households: a systematic review and meta-analysis

Front Med (Lausanne). 2026 Sep 4;13:1818895. doi: 10.3389/fmed.2026.1818895. eCollection 2026.ABSTRACTBACKGROUND: Out-of-pocket expenditure (OOPE) on medicines constitutes a substantial component of healthcare spending in India, particularly among patients with chronic diseases requiring continuous