J Transl Med. 2026 Feb 2. doi: 10.1186/s12967-026-07775-1. Online ahead of print.ABSTRACTBACKGROUND: Pazopanib, a multi-targeted tyrosine kinase inhibitor, is employed in the treatment of various malignancies, including metastatic non-adipocytic soft tissue sarcoma.METHODS: This systematic review an
Saudi Med J. 2026 Jan;47(1):120-177. doi: 10.15537/smj.2026.47.1.20250578.ABSTRACTOBJECTIVES: To develop an evidence-based clinical guideline for the prevention and management of cardiovascular diseases (CVDs) in Saudi Arabia, tailored to local epidemiology and healthcare needs.METHODS: A multidisci
Adv Ther. 2026 Feb 2. doi: 10.1007/s12325-026-03497-4. Online ahead of print.ABSTRACTINTRODUCTION: Pulmonary arterial hypertension (PAH) is a progressive, often fatal disease characterized by an elevation in pulmonary arterial pressure and pulmonary vascular resistance (PVR). Oral treprostinil is in
Case Rep Obstet Gynecol. 2026 Jan 29;2026:9549502. doi: 10.1155/crog/9549502. eCollection 2026.ABSTRACTOBJECTIVE: Uterine leiomyoma represents one of the most common pathologies affecting women of reproductive age, often presenting with lower abdominal pain and abnormal bleeding. Benign metastasisin
Iran J Pathol. 2026;21(1):29-40. doi: 10.30699/ijp.2025.2052015.3407. Epub 2025 Nov 11.ABSTRACTBACKGROUND & OBJECTIVE: Adrenal tumors present a notable prevalence of 4-7% in individuals above 40 years old. Current guidelines recommend adrenalectomy for hormone-secreting, potentially malignant, or la
JHEP Rep. 2025 Nov 29;8(2):101699. doi: 10.1016/j.jhepr.2025.101699. eCollection 2026 Feb.ABSTRACTBACKGROUND & AIMS: Transjugular intrahepatic portosystemic shunt (TIPS) is an established treatment for complications of portal hypertension (variceal bleeding and refractory ascites). Sarcopenia affect
Front Cardiovasc Med. 2026 Jan 16;12:1705102. doi: 10.3389/fcvm.2025.1705102. eCollection 2025.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICI) have markedly improved the prognosis of numerous malignancies; however, they are also associated with a broad spectrum of immune-related adverse event
Transl Psychiatry. 2026 Jan 31. doi: 10.1038/s41398-026-03820-1. Online ahead of print.ABSTRACTCognitive deficits across multiple domains are prevalent in patients with schizophrenia (PWS), and metabolic syndrome (MetS) may significantly contribute to this impairment. To clarify the complex relation
Neurochirurgie. 2026 Jan 30;72(2):101779. doi: 10.1016/j.neuchi.2026.101779. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Unplanned 30-day readmission after elective treatment of unruptured intracranial aneurysms (UCAs) represents a significant clinical and economic burden. Reported read
Clin Exp Nephrol. 2026 Jan 31. doi: 10.1007/s10157-026-02821-0. Online ahead of print.ABSTRACTBACKGROUND: Effectively managing a large numbers chronic kidney disease (CKD) cases requires collaboration between nephrologists and non-nephrologists. In 2024, the Japan physicians association conducted a
BMC Prim Care. 2026 Jan 30. doi: 10.1186/s12875-026-03188-7. Online ahead of print.ABSTRACTBACKGROUND: Atrial fibrillation (AF) is a common, often silent, arrhythmia that markedly increases stroke risk yet remains undiagnosed in many high-risk adults. Mobile electrocardiogram technology in community
Clin Transplant. 2026 Feb;40(2):e70462. doi: 10.1111/ctr.70462.ABSTRACTBACKGROUND: Acute kidney injury frequently complicates the end stages of liver diseases, worsening the condition of patients waiting for liver transplants. Continuous renal replacement therapy during liver transplant is still a l
Neurol Neurochir Pol. 2026 Jan 30. doi: 10.5603/pjnns.109813. Online ahead of print.ABSTRACTINTRODUCTION: Intracranial hemorrhage (ICH) after surgical evacuation of chronic subdural hematoma (cSDH) is a rare but serious complication associated with considerable morbidity and mortality. This review a
J Clin Hypertens (Greenwich). 2026 Feb;28(2):e70199. doi: 10.1111/jch.70199.ABSTRACTA recent survey in the Philippines, PRESYON-4, showed increasing prevalence of hypertension from 22% in the 1990s to 37% in 2021, of which only 52% were aware of their diagnosis. While rates of treatment and adherenc
Sci Rep. 2026 Jan 30. doi: 10.1038/s41598-026-36702-z. Online ahead of print.ABSTRACTThe level and predictors of medication adherence have not been given attention among populations for whom the cost of treatment is not a concern, especially in the Ghanaian healthcare setting. This study compared ge
BMJ Open. 2026 Jan 29;16(1):e097874. doi: 10.1136/bmjopen-2024-097874.ABSTRACTOBJECTIVES: Digital technology in primary healthcare service delivery can enhance accessibility, service delivery and health outcomes in rural populations. The objective of this systematic review is to review and synthesis
J Cardiovasc Surg (Torino). 2026 Jan 29. doi: 10.23736/S0021-9509.25.13502-7. Online ahead of print.ABSTRACTINTRODUCTION: Coral reef aorta (CRA) is a rare condition characterized by exophytic, heavily calcified aortic stenoses. Limited evidence is available concerning epidemiology, pathophysiology a
Minerva Gastroenterol (Torino). 2026 Jan 29. doi: 10.23736/S2724-5985.25.04054-9. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) is a complex and multifactorial condition that represents a major global health challenge. It is characterized by a cluster of interrelated metabolic abnormalitie
Blood Press. 2026 Jan 29:1-20. doi: 10.1080/08037051.2026.2624257. Online ahead of print.ABSTRACTBACKGROUND: Effective management of arterial hypertension remains a major global health priority due to its high prevalence and substantial burden of cardiovascular (CV) and renal complications. In respo
Zhonghua Yu Fang Yi Xue Za Zhi. 2026 Feb 6;60(2):259-269. doi: 10.3760/cma.j.cn112150-20250408-00292.ABSTRACTAntiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by clinical manifestations such as thrombocytopenia, thrombosis, and miscarriage caused by persistent positive a
Pharmacotherapy. 2026 Feb;46(2):e70110. doi: 10.1002/phar.70110.ABSTRACTCancer therapy-induced cardiotoxicity (CTIC) is a significant clinical challenge in an era of rapidly evolving oncologic treatment. This comprehensive narrative review synthesizes evidence from clinical trials, meta-analyses, an
Clin Pharmacokinet. 2026 Jan 29. doi: 10.1007/s40262-026-01618-4. Online ahead of print.ABSTRACTBACKGROUND: High-dose methotrexate (HDMTX) is a key treatment for lymphoma with central nervous system involvement. Whether incorporating cystatin C into glomerular filtration rate estimation improves met
Eur J Prev Cardiol. 2026 Jan 28:zwag052. doi: 10.1093/eurjpc/zwag052. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Susceptibility to hypertension-mediated organ damage (HMOD) is influenced by genetics, age, gender, and additional cardiovascular risk factors and comorbidities in the individual p
Stroke. 2026 Jan 28. doi: 10.1161/STR.0000000000000514. Online ahead of print.ABSTRACTStroke remains a rare but life-threatening complication of pregnancy, with significant implications for both maternal and fetal health. Current stroke prevention and treatment guidelines offer limited guidance for
