Exploring Associations Among Loneliness, Depression, and Cardiovascular Risk Factors in a Free Medical Clinic: A Cross-Sectional Pilot Study

Cureus. 2026 Jul 17;18(7):e112855. doi: 10.7759/cureus.112855. eCollection 2026 Jul.ABSTRACTIntroduction Depression and loneliness have been linked to cardiovascular disease (CVD), but few studies explore their combined impact. Loneliness has been identified as an independent CVD risk factor, while

Autoimmune thyroiditis in pregnancy: epidemiology, clinical impact, and contemporary management challenges

J Med Life. 2026 Jun;19(6):426-432. doi: 10.25122/jml-2026-0019.ABSTRACTAutoimmune thyroiditis represents the most common cause of thyroid dysfunction in women of reproductive age and is frequently encountered during pregnancy. The presence of thyroid autoantibodies, particularly anti-thyroid peroxi

Blood pressure and renal outcomes after renal denervation in patients with chronic kidney disease: A systematic review and meta-analysis

Medicine (Baltimore). 2026 Aug 14;105(33):e50220. doi: 10.1097/MD.0000000000050220.ABSTRACTBACKGROUND: This systematic review and meta-analysis aimed to evaluate the efficacy and safety of renal denervation (RDN) in patients with chronic kidney disease (CKD), including those with end-stage renal dis

Survodutide for Obesity in Chinese Adults: Phase 3 Randomized Trial Design and Baseline Characteristics (SYNCHRONIZE™-CN)

Diabetes Ther. 2026 Aug 14. doi: 10.1007/s13300-026-01908-x. Online ahead of print.ABSTRACTINTRODUCTION: We aimed to describe the rationale, design, and overall baseline characteristics of the trial evaluating the efficacy, safety, and tolerability of survodutide in Chinese adults with overweight or

Postpartum blood pressure monitoring and management: Critical findings from an expert convening

Pregnancy (Hoboken). 2026 Jan 14;2(1):e70223. doi: 10.1002/pmf2.70223. eCollection 2026 Jan.ABSTRACTHypertensive disorders of pregnancy (HDP) are significant contributors to maternal morbidity and mortality, impacting an estimated 15.9% of delivery hospitalizations in the United States. More than 50

A Case of Recurrent Refractory Stomal Variceal Bleeding Associated with Oxaliplatin-Induced Portal Hypertension

Surg Case Rep. 2026;12(1):26-0400. doi: 10.70352/scrj.cr.26-0400. Epub 2026 Aug 6.ABSTRACTINTRODUCTION: Stomal variceal bleeding is a rare but potentially life-threatening complication in patients with gastrointestinal stomas complicated by portal hypertension. Although oxaliplatin-based chemotherap

Current status of cardiovascular risk factor control: are we meeting the targets?

Curr Probl Cardiol. 2026 Aug 12;51(11):103428. doi: 10.1016/j.cpcardiol.2026.103428. Online ahead of print.ABSTRACTControl of cardiovascular risk factors remains suboptimal worldwide, despite advances in pharmacologic therapies and evidence-based guidelines. Key modifiable determinants such as hyper

Hypertensive disorders of pregnancy: A review and updates for the emergency physician

Am J Emerg Med. 2026 Aug 6;110:54-61. doi: 10.1016/j.ajem.2026.07.066. Online ahead of print.ABSTRACTHypertensive disorders of pregnancy (HDPs) are a spectrum of disease contributing to immediate and lasting morbidity and mortality in pregnant patients and neonates globally. With decreasing access t

Electrochemiluminescence immunoassay for quantifying ZMA001 in human serum: method development, validation, and clinical pharmacokinetic application

Bioanalysis. 2026 Aug 12:1-9. doi: 10.1080/17576180.2026.2715919. Online ahead of print.ABSTRACTZMA001 is a novel human IgG1 monoclonal antibody (mAb) specifically designed to target the N-terminal region of transmembrane lysyl-tRNA synthetase 1 (KARS1), an enzyme implicated in the pathobiology of p

Can pilocarpine effectively and safely manage glaucoma in the modern era? A systematic review and meta-analysis

Naunyn Schmiedebergs Arch Pharmacol. 2026 Aug 11. doi: 10.1007/s00210-026-05571-8. Online ahead of print.ABSTRACTThis study systematically evaluates the efficacy, safety, tolerability, and contemporary clinical positioning of topical pilocarpine in the management of glaucoma and ocular hypertension.

Barriers to Hepatitis B Treatment: A Multicentre Cross-Sectional Registry and Survey Study by the Canadian Hepatitis B Network

Liver Int. 2026 Sep;46(9):e70835. doi: 10.1111/liv.70835.ABSTRACTBACKGROUND & AIMS: Chronic hepatitis B (CHB) remains a leading cause of cirrhosis and hepatocellular carcinoma (HCC) worldwide, yet treatment uptake is suboptimal even in high-resource settings. This pan-Canadian study aimed to quantif

Practice nurse management of hypertension in primary care: a scoping review

Prim Health Care Res Dev. 2026 Aug 11;27:e89. doi: 10.1017/S1463423626101455.ABSTRACTAIM: To review the current diagnosis and treatment of hypertension (HTN) and explore alternative care management options.BACKGROUND: HTN is underdiagnosed and poorly managed in the UK. With an increasing emphasis on

Large saccular aneurysms of the vertebrobasilar arteries with segmental chronic mural ectasia: A case report and review of management strategies

Qatar Med J. 2026 Jun 22;2026(2):46. doi: 10.5339/qmj.2026.46. eCollection 2026.ABSTRACTBACKGROUND: Large saccular aneurysms of the basilar artery associated with chronic mural ectasia are rare and difficult to manage because of their high risk of thrombus formation and rupture. We present a case th

Pulmonary hypertension and acute hypoxic respiratory failure in preterm neonates

J Perinatol. 2026 Aug 8. doi: 10.1038/s41372-026-02858-9. Online ahead of print.ABSTRACTPulmonary hypertension (PH) in preterm infants is a complex and heterogeneous condition that significantly contributes to hypoxic respiratory failure (HRF), bronchopulmonary dysplasia (BPD), and mortality. Unlike

Comparative Efficacy and Safety of Antihypertensive Strategies in Diabetic Kidney Disease: Protocol for an Update of a Systematic Review and Component Network Meta-Analysis

Health Sci Rep. 2026 Aug 6;9(8):e73020. doi: 10.1002/hsr2.73020. eCollection 2026 Aug.ABSTRACTBACKGROUND AND AIMS: Chronic kidney disease (CKD) is a significant global contributor to morbidity and mortality, with hypertension and diabetes mellitus remaining its primary causes. Effective antihyperten

STOP-RIO study: protocol for a randomised, controlled, open-label non-inferiority trial to test the safety of discontinuation of riociguat after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension

BMJ Open. 2026 Aug 7;16(8):e120820. doi: 10.1136/bmjopen-2026-120820.ABSTRACTINTRODUCTION: Balloon pulmonary angioplasty (BPA) improves haemodynamics and outcomes in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Riociguat is frequently initiated before BPA to reduce

A content analysis of global and national policies, plans, and guidelines to integrate NCDs with HIV care in LMICs

PLOS Glob Public Health. 2026 Aug 7;6(8):e0007072. doi: 10.1371/journal.pgph.0007072. eCollection 2026.ABSTRACTThe growing burden of non-communicable diseases (NCDs) among people living with HIV (PWH) in low- and middle-income countries (LMICs), threatens gains in life expectancy. Global organizatio

Economic evaluations of hypertension interventions in pregnancy lack standardisation: results of a systematic review

Value Health. 2026 Aug 6:S1098-3015(26)02569-6. doi: 10.1016/j.jval.2026.06.025. Online ahead of print.ABSTRACTOBJECTIVES: Hypertensive disorders of pregnancy (HDP), including pre-eclampsia, pose lifelong health risks for women and infants. While HDP interventions are increasingly evaluated for cost

Health system competence and care continuity in patients with hypertension: electronic cohort in Uruguay

Blood Press. 2026 Dec;35(1):2702689. doi: 10.1080/08037051.2026.2702689. Epub 2026 Aug 9.ABSTRACTBACKGROUND: Despite efforts to improve hypertension management, control rates remain low. Effective control depends on care competence and continuity. We describe health system competence, care continuit

Safety and efficacy of low-cost, off-label balloons during balloon-occluded retrograde transvenous obliteration procedure

J Clin Imaging Sci. 2026 Jul 28;16:28. doi: 10.25259/JCIS_232_2025. eCollection 2026.ABSTRACTOBJECTIVES: The objective of the study is to assess the technical feasibility, safety, and clinical efficacy of balloon-occluded retrograde transvenous obliteration (BRTO) using low-cost, off-label balloon c

Prevalence, treatment rates and control of dyslipidemia among diabetes patients in northern Nigeria: A cross-sectional, multicenter study

PLoS One. 2026 Aug 5;21(8):e0346350. doi: 10.1371/journal.pone.0346350. eCollection 2026.ABSTRACTOBJECTIVES: Dyslipidemia is prevalent among Nigerians with diabetes mellitus (DM), but its treatment has not been well-studied. The objective of this study was to determine the prevalence, treatment rate

Treatment Strategies in Incident and Recurrent Hyperkalemia: Insights from the TRACK Study

Adv Ther. 2026 Aug 5. doi: 10.1007/s12325-026-03666-5. Online ahead of print.ABSTRACTINTRODUCTION: Little is known about the implementation of guideline recommendations and healthcare provider decision-making when managing hyperkalemia. We aimed to address these knowledge gaps and better understand

Cardiovascular Risk and Blood Pressure Control in Patients with Diabetes at Federally Qualified Health Centers: Baseline Findings from the Office-GAP IMPACT (Office-Guidelines Applied to Practice Improving Diabetic Patients' Adherence to Treatment and Prevention of Cardiovascular Disease) Program

J Racial Ethn Health Disparities. 2026 Aug 5. doi: 10.1007/s40615-026-03143-3. Online ahead of print.ABSTRACTBACKGROUND: The rate of diabetes and blood pressure (BP) control are low, particularly in patients with diabetes receiving care from federally qualified health centers (FQHCs). The Office-Gap

Hypertension treatment and risk of cardiovascular disease or mortality across risk equations: results from SPRINT

J Hypertens. 2026 Jul 23. doi: 10.1097/HJH.0000000000004397. Online ahead of print.ABSTRACTThe 2025 AHA/ACC blood pressure (BP) management guidelines recommend BP treatment for 10-year cardiovascular disease (CVD) ≥7.5% from the PREVENT equation, replacing the prior pooled cohort equations (PCE). We