The Use of Pulmonary Vasodilators in Pediatric Patients with Single-Ventricle Palliation: A Ten-Year Experience in a Tertiary Care Center

Pediatr Cardiol. 2025 May 10. doi: 10.1007/s00246-025-03887-5. Online ahead of print.ABSTRACTIn single-ventricle circulation, pulmonary vascular resistances (PVR) play a crucial role at various stages of surgical palliation. Increased PVR detected at cardiac catheterization represents a contraindica

Transcatheter Aortic Valve Replacement With Intra-Annular Self-Expanding or Balloon-Expandable Valves: The Multicenter International NAVULTRA Registry

JACC Cardiovasc Interv. 2025 May 5:S1936-8798(25)00923-9. doi: 10.1016/j.jcin.2025.03.015. Online ahead of print.ABSTRACTBACKGROUND: No comparative data exist with the self-expanding Navitor (NAV) and the balloon-expandable SAPIEN 3 Ultra (ULTRA) transcatheter heart valves (THVs).OBJECTIVES: This st

Trends and Disparities in Heart Failure Mortality Among Hypertensive Older Adults in the United States: A 22-Year Retrospective Study

J Clin Hypertens (Greenwich). 2025 May;27(5):e70064. doi: 10.1111/jch.70064.ABSTRACTHypertension (HTN) is a significant risk factor for heart failure (HF), and both significantly contribute to cardiovascular mortality. This study aims to examine trends and disparities in HF-related mortality among h

Photoplethysmography-Derived Arterial Stiffness Index Delivered Greater Cardiovascular Prevention Value to Non-Elderly: A Retrospective Cohort Study Based on UK Biobank

J Clin Hypertens (Greenwich). 2025 May;27(5):e70058. doi: 10.1111/jch.70058.ABSTRACTPhotoplethysmography-derived arterial stiffness index (ASI) has been proven to be associated with various cardiovascular diseases. The present study aims to determine whether the predictive value of ASI varies betwee

Loganin ameliorates left ventricular fibrosis and dysfunction induced by pressure overload via the Sirt1/AKT/TGF-β1 signaling pathway

J Nat Med. 2025 May 10. doi: 10.1007/s11418-025-01911-9. Online ahead of print.ABSTRACTLoganin (LG), a natural compound derived from Cornus officinalis Sieb. et Zucc., possesses diverse pharmacological properties, such as anti-inflammatory, anti-hypertrophic, and antioxidant effects. However, the ro

Functional analysis of JPH2-knockout cardiomyocytes identifies ECCD as a novel indicator in a human cardiac modelJPH2

Stem Cell Res Ther. 2025 May 9;16(1):234. doi: 10.1186/s13287-025-04323-4.ABSTRACTBACKGROUND: Junctophilin-2 (JPH2) is a vital protein in cardiomyocytes, anchoring T-tubule and sarcoplasmic reticulum membranes to facilitate excitation-contraction coupling, a process essential for cardiac contractile

"Low-to-moderate arsenic exposure: a global systematic review of cardiovascular disease risks"

Environ Health. 2025 May 9;24(1):29. doi: 10.1186/s12940-025-01184-5.ABSTRACTHigh arsenic (As) exposure (≥ 100 µg/l) is associated with cardiovascular (CVD) outcomes, however, the CVD risk from low-to-moderate As exposure (< 100 µg/l) has been less explored. There is a paucity of systematic reviews

Life's Essential 8 cardiovascular health, cardiovascular-kidney-metabolic syndrome stages, and incident cardiovascular events: a nationwide 10-year prospective cohort study in China

Cardiovasc Diabetol. 2025 May 9;24(1):197. doi: 10.1186/s12933-025-02735-3.ABSTRACTBACKGROUND: Definition and staging rationale of cardiovascular-kidney-metabolic syndrome were developed. The utility of cardiovascular-kidney-metabolic construct in risk stratification and target strategies of health

Effects of empagliflozin on functional capacity, LV filling pressure, and cardiac reserves in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction: a randomized controlled open-label trial

Cardiovasc Diabetol. 2025 May 9;24(1):196. doi: 10.1186/s12933-025-02756-y.ABSTRACTBACKGROUND: Clinical trials have established the prognostic benefits of sodium‒glucose cotransporter 2 (SGLT2) inhibitors in patients with type 2 diabetes mellitus (T2DM) and heart failure (HF) with preserved ejection

Associations between triglyceride-glucose body mass index and all-cause mortality in ICU patients with sepsis and acute heart failure

BMC Cardiovasc Disord. 2025 May 9;25(1):359. doi: 10.1186/s12872-025-04804-7.ABSTRACTBACKGROUND: The triglyceride‒glucose body mass index (TyG-BMI) has been recognized as a significant predictor of cardiovascular disease risk and plays a crucial role in assessing insulin resistance. However, the cor

Linking cardiometabolic multimorbidity to depressive symptoms in the oldest-old: results from a cross-sectional study in Germany

BMC Public Health. 2025 May 9;25(1):1720. doi: 10.1186/s12889-025-22964-1.ABSTRACTBACKGROUND: Depression often accompanies cardiometabolic multimorbidity (CMM), but it remains unclear whether this association persists in very old people. Hence, we examined the link between CMM and depressive symptom

Splenic and portal venous flow associated with frailty and sarcopenia in older outpatients with cardiovascular disease

BMC Geriatr. 2025 May 9;25(1):319. doi: 10.1186/s12877-025-05973-y.ABSTRACTBACKGROUND: Older patients with cardiovascular disease often experience frailty and sarcopenia. We evaluated whether a reduced blood flow in the splenic and portal vein is associated with frailty and sarcopenia in older patie

Response to letter to editor, sex disparities in mental distress, selfcare ability, and quality of life in patients with chronic heart failure

No abstractHeart Vessels. 2025 May 9. doi: 10.1007/s00380-025-02552-4. Online ahead of print.NO ABSTRACTPMID:40346372 | DOI:10.1007/s00380-025-02552-4

Arrhythmic burden of long-term postsurgical hypoparathyroidism assessed with 24-hour Holter ECG

Endocrine. 2025 May 9. doi: 10.1007/s12020-025-04235-6. Online ahead of print.ABSTRACTPURPOSE: Postsurgical hypoparathyroidism is associated with an increased cardiovascular risk, however an increased arrhythmic risk in this population is controversial.METHODS: Twenty-two postmenopausal women with p

Purine xanthine oxidase inhibitors are not conducive to the prognosis of chronic heart failure: a meta-analysis

Eur J Clin Pharmacol. 2025 May 10. doi: 10.1007/s00228-025-03848-0. Online ahead of print.ABSTRACTBACKGROUND: According to previous studies, the efficacy of xanthine oxidase inhibitors (XOIs) in patients with chronic heart failure (CHF) is still controversial. Therefore, the purpose of this study wa

Acute pulmonary embolism: a paradigm shift in interventional treatment and interdisciplinary care?

Eur Radiol. 2025 May 9. doi: 10.1007/s00330-025-11548-7. Online ahead of print.ABSTRACTCatheter-based recanalization procedures have long been standard of care in treating myocardial infarction and stroke. Interventional treatments for pulmonary embolism (PE), however, have only been performed occas

Association between triglyceride-glucose index and all cause mortality in critically ill patients with heart failure

Sci Rep. 2025 May 9;15(1):16157. doi: 10.1038/s41598-025-00129-9.ABSTRACTThe triglyceride-glucose (TyG) index is regarded as a surrogate marker of systemic insulin resistance (IR). Studies have substantiated the impact of IR on cardiovascular diseases. Nonetheless, the prognostic value of the TyG in

Bulimia Nervosa and Risk of Cardiovascular Outcomes: A Longitudinal Matched Cohort Study in Taiwan

Int J Eat Disord. 2025 May 9. doi: 10.1002/eat.24461. Online ahead of print.ABSTRACTOBJECTIVE: Bulimia nervosa (BN), a prevalent eating disorder characterized by recurrent binge-purge cycles, may contribute to long-term cardiovascular (CV) complications. However, evidence regarding these outcomes re

Metabolic syndrome severity score and long-term cardiovascular outcomes in patients with myocardial infarction with nonobstructive coronary arteries

Nutr Metab Cardiovasc Dis. 2025 Apr 25:104104. doi: 10.1016/j.numecd.2025.104104. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Metabolic syndrome (MetS) is a cluster of metabolic disorders that promotes the risk of cardiovascular diseases. Beyond the dichotomous criteria of MetS, a continuous M

Environmental pollution and cardiovascular health. Challenges and new perspectives

Clin Investig Arterioscler. 2025 May 8:500802. doi: 10.1016/j.arteri.2025.500802. Online ahead of print.ABSTRACTEnvironmental pollution is a key factor in cardiovascular disease (CVD) development. Several evidences support its impact at the pathophysiology of arteriosclerosis, highlighting the role

Caregivers' impact in heart failure: a cross-sectional study

BMJ Support Palliat Care. 2025 May 9:spcare-2024-005262. doi: 10.1136/spcare-2024-005262. Online ahead of print.ABSTRACTOBJECTIVES: Caregivers play a pivotal role in supporting patients with heart failure (HF). Caregiving may be associated with significant impact on the caregivers' health. This stud

Addressing Cardiovascular Diseases Challenges in South Korea: Strategies to Improve Outcomes

Korean Circ J. 2025 Apr 7. doi: 10.4070/kcj.2024.0385. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) pose a significant public health challenge in South Korea. This paper attempts to assess the current status of major cardiovascular risk factors and representative CVDs, and proposes p

Prognostic Value of Plasma Big Endothelin-1 in Patients Hospitalized for Heart Failure

Korean Circ J. 2025 Apr 11. doi: 10.4070/kcj.2024.0354. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Endothelin-1 (ET-1) is a potent vasoconstrictor and multifunctional neuroendocrine hormone that is closely associated with the pathophysiology of heart failure (HF). Currently, the eviden

Transcatheter Repair of a Sinus Venosus Defect With a Modified Harmony Transcatheter Pulmonary Valve Prosthesis

JACC Case Rep. 2025 May 7;30(9):103294. doi: 10.1016/j.jaccas.2025.103294. Epub 2025 Feb 26.ABSTRACTTranscatheter repair of sinus venosus atrial septal defect (SVASD) with partial anomalous pulmonary venous return (PAPVR) has become an acceptable surgical alternative for appropriately selected patie