Machine learning approaches for predicting heart failure readmissions

Postgrad Med J. 2025 Jul 6:qgaf102. doi: 10.1093/postmj/qgaf102. Online ahead of print.ABSTRACTPURPOSE: This study aims to develop and evaluate machine learning (ML) models to predict the likelihood of hospital readmission within 30 days after discharge for patients with heart failure (HF). The goal

C-Reactive Protein-Albumin-Lymphocyte (CALLY) Index and Length of Hospital Stay in Patients With Heart Failure

No abstractAngiology. 2025 Jul 5:33197251355348. doi: 10.1177/00033197251355348. Online ahead of print.NO ABSTRACTPMID:40618202 | DOI:10.1177/00033197251355348

Role of Col1a2 and Postn in left ventricular noncompaction cardiomyopathy

J Cardiothorac Surg. 2025 Jul 5;20(1):287. doi: 10.1186/s13019-025-03509-4.ABSTRACTBACKGROUND: Left ventricular noncompaction cardiomyopathy (LVNC) is a rare myocardial developmental anomaly characterized by incomplete myocardial compact layer development in the left ventricular wall, resulting in a

Efficacy and clinical outcomes of bone-marrow mononuclear cell therapy in chronic heart failure: a systemic review and meta-analysis

BMC Cardiovasc Disord. 2025 Jul 5;25(1):486. doi: 10.1186/s12872-025-04938-8.ABSTRACTBACKGROUND: Over the past decade, there has been no clear evidence regarding the comparative effectiveness of bone-marrow mononuclear cell (BMMNC) therapy in patients with chronic heart failure (HF).METHODS: We retr

Exploring sex-specific clinical features in Chinese patients with Takotsubo syndrome

BMC Cardiovasc Disord. 2025 Jul 5;25(1):490. doi: 10.1186/s12872-025-04788-4.ABSTRACTBACKGROUND: Takotsubo syndrome (TTS) is considered as a transient acute heart failure syndrome predominant in females. However, data on Chinese TTS patients are limited. Therefore, this study aimed to investigate th

Klotho modulation by tempol: a potential therapeutic axis in sepsis

BMC Cardiovasc Disord. 2025 Jul 5;25(1):492. doi: 10.1186/s12872-025-04738-0.ABSTRACTBACKGROUND: Sepsis is characterized by massive inflammatory and oxidative stress responses. The imbalance between oxidant and antioxidant activities during sepsis contributes to hyperinflammation, oxidation, endothe

Splenic artery aneurysmal rupture at 24 weeks gestation in a patient with successful in vitro fertilization and embryo transfer after kidney transplantation: a case report

BMC Nephrol. 2025 Jul 5;26(1):355. doi: 10.1186/s12882-025-04285-y.ABSTRACTBACKGROUND: Kidney transplantation represents a critical intervention for end-stage renal disease on a global scale. Many women of childbearing age who have received a kidney transplant express a significant desire to conceiv

TSLP mitigates post-infarction myocardial remodeling by promoting eosinophil recruitment and inhibiting JAK1-STAT5-mediated ferroptosis

Apoptosis. 2025 Jul 5. doi: 10.1007/s10495-025-02137-6. Online ahead of print.ABSTRACTAcute myocardial infarction (AMI) remains a leading cause of morbidity and mortality globally, often leading to heart failure due to excessive inflammation and fibrosis. Thymic stromal lymphopoietin (TSLP), a cytok

REMOVED: The Pharmacokinetics and Pharmacodynamics of Distally-Timed Eatg in Allogeneic Hematopoietic Cell Transplantation Conditioning

Transplant Cell Ther. 2025 Feb;31(2S):S174-S175. doi: 10.1016/j.jtct.2025.01.269. Epub 2025 Feb 26.ABSTRACTThis abstract has been removed: please see Elsevier policy on article withdrawal (https://www.elsevier.com/about/policies-and-standards/article-withdrawal). This article has been removed at the

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography and for Heart Failure With Preserved Ejection Fraction Diagnosis: An Update From the American Society of Echocardiography

J Am Soc Echocardiogr. 2025 Jul;38(7):537-569. doi: 10.1016/j.echo.2025.03.011.ABSTRACTEchocardiographic assessment of left ventricular (LV) diastolic function is an integral part of the routine evaluation of patients presenting with symptoms of dyspnea or clinical concerns for heart failure. Given

Impact of left ventricular end-diastolic pressure on clinical outcomes in patients with ST-elevation myocardial infarction (Hunter LVEDP Study): a prospective, single-centre study

BMJ Open. 2025 Jul 5;15(7):e090465. doi: 10.1136/bmjopen-2024-090465.ABSTRACTOBJECTIVES: Elevated left ventricular end-diastolic pressure (LVEDP) in ST-segment elevation myocardial infarction (STEMI) has been studied in patients who received thrombolysis or who were treated early in the primary perc

Determinants of mid-term response to left bundle branch pacing in heart failure patients with left bundle branch block

Can J Cardiol. 2025 Jul 3:S0828-282X(25)00528-8. doi: 10.1016/j.cjca.2025.06.071. Online ahead of print.ABSTRACTBACKGROUND: Response to left bundle branch pacing (LBBP) varies in patients with left bundle branch block (LBBB). We aimed to investigate whether clinical response to LBBP was associated w

Real-world comparative effectiveness of angiotensin-neprilysin inhibition versus angiotensin receptor blockers in acute myocardial infarction

Int J Cardiol. 2025 Jul 3:133543. doi: 10.1016/j.ijcard.2025.133543. Online ahead of print.ABSTRACTBACKGROUND: Angiotensin-neprilysin inhibition (ARNI) reduces mortality and morbidity in chronic heart failure, but its efficacy in acute myocardial infarction (MI) remains uncertain. This study compare

Endothelial dysfunction assessed by the endothelial activation and stress index (EASIX) predicts risk of mortality in chronic heart failure patients

Int J Cardiol. 2025 Jul 3:133566. doi: 10.1016/j.ijcard.2025.133566. Online ahead of print.ABSTRACTBACKGROUND: Endothelial dysfunction accompanies chronic heart failure (CHF) but is hard to quantify in routine practice. The Endothelial Activation and Stress Index (EASIX), calculated from creatinine,

The Therapeutic Potential of Adiponectin and Extracellular Vesicles for Promoting Improved Healthspan

Ageing Res Rev. 2025 Jul 3:102823. doi: 10.1016/j.arr.2025.102823. Online ahead of print.ABSTRACTThe gradual decline in physiological functions that comes with aging contributes to a range of chronic diseases, such as Alzheimer's, type 2 diabetes, heart failure, and osteoarthritis. Significant advan

Evolving training paradigms: The critical need for advanced heart failure in the contemporary CICU

No abstractJ Card Fail. 2025 Jul 3:S1071-9164(25)00283-0. doi: 10.1016/j.cardfail.2025.05.016. Online ahead of print.NO ABSTRACTPMID:40617311 | DOI:10.1016/j.cardfail.2025.05.016

Human Use Conditions in Fatigue of Intravenous Leads Used in Cardiac Implanted Electronic Devices

Heart Rhythm. 2025 Jul 3:S1547-5271(25)02628-1. doi: 10.1016/j.hrthm.2025.06.050. Online ahead of print.ABSTRACTBACKGROUND: Transvenous lead conductors are subject to fatigue fracture from repetitive bending stresses, which are proportional to alternating curvature. A prerequisite for developing a v

Risk factors for severe morbidity and mortality: a French, nationwide study of 375,075 pelvic organ prolapse operations

Eur J Obstet Gynecol Reprod Biol. 2025 Jul 3;312:114561. doi: 10.1016/j.ejogrb.2025.114561. Online ahead of print.ABSTRACTINTRODUCTION: Pelvic organ prolapse (POP) affects a woman's quality of life. Although the surgical treatment of POP is becoming increasingly common, data on early post-operative

Xanthine oxidase inhibitor allopurinol preserves cardiac function after experimental malocclusion induced by occlusal disharmony in mice

J Physiol Sci. 2025 Jun 29;75(2):100029. doi: 10.1016/j.jphyss.2025.100029. Online ahead of print.ABSTRACTOxidative stress caused by poor oral condition is associated with systemic diseases, including cardiovascular disease. In this work, therefore, we examined the effect of allopurinol, an inhibito

Developing a Panel of Shared Susceptibility Genes as Diagnostic Biomarkers for chronic obstructive pulmonary disease and Heart Failure

Comput Biol Med. 2025 Jul 4;196(Pt A):110657. doi: 10.1016/j.compbiomed.2025.110657. Online ahead of print.ABSTRACTAIM: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are closely intertwined comorbidities that present significant clinical challenges due to the poorly understood

Exploring advanced deep learning approaches in cardiac image analysis: A comprehensive review

Comput Biol Med. 2025 Jul 4;196(Pt A):110708. doi: 10.1016/j.compbiomed.2025.110708. Online ahead of print.ABSTRACTBACKGROUND: Cardiac image analysis plays an important role in detecting and categorizing cardiovascular diseases (CVDs), such as coronary artery disease (CAD), heart failure, congenital

Mineralocorticoid Receptor Antagonists in Myocardial Infarction Patients: A Systematic Review and Meta-Analysis of Randomized Trials

JACC Heart Fail. 2025 Jul 4;13(9):102531. doi: 10.1016/j.jchf.2025.102531. Online ahead of print.ABSTRACTBACKGROUND: It is unclear whether routine mineralocorticoid antagonist (MRA) use benefits all post-myocardial infarction (MI) patients.OBJECTIVES: This study aims to perform a systematic review a

Mineralocorticoid Receptor Antagonists in Post-Myocardial Infarction Patients: An Old Relationship Revisited?

No abstractJACC Heart Fail. 2025 Jul 4;13(9):102521. doi: 10.1016/j.jchf.2025.102521. Online ahead of print.NO ABSTRACTPMID:40616941 | DOI:10.1016/j.jchf.2025.102521

Evaluating the Performance and Potential Bias of Predictive Models for Detection of Transthyretin Cardiac Amyloidosis

JACC Adv. 2025 Jul 4;4(8):101901. doi: 10.1016/j.jacadv.2025.101901. Online ahead of print.ABSTRACTBACKGROUND: Delays in the diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM) contribute to the significant morbidity of the condition, especially in the era of disease-modifying therapies. Scr