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Es. | Hearth Failure

Risk of Cardiorespiratory Events Following Respiratory Syncytial Virus-Related Hospitalization

JAMA Netw Open. 2026 Feb 2;9(2):e2556767. doi: 10.1001/jamanetworkopen.2025.56767.ABSTRACTIMPORTANCE: Respiratory syncytial virus (RSV) may trigger cardiorespiratory events in adults.OBJECTIVE: To assess the risk of cardiorespiratory events in the 180 days following RSV-related hospitalization compa

Heart failure with preserved ejection fraction: a systemic condition of comorbidities

No abstractHeart Fail Rev. 2026 Feb 3;31(1):22. doi: 10.1007/s10741-025-10586-z.NO ABSTRACTPMID:41632351 | DOI:10.1007/s10741-025-10586-z

Hyponatraemia in heart failure: a mechanistic approach to contemporary management

Heart Fail Rev. 2026 Feb 3;31(1):23. doi: 10.1007/s10741-026-10595-6.ABSTRACTHyponatraemia remains the most prevalent electrolyte disturbance in heart failure, complicating clinical management and correlating with adverse outcomes. While traditionally viewed as a biomarker of disease severity, mount

Prediction of Fontan failure and correlates of Fontan-associated liver disease severity using machine learning and radiomic features from multi-parametric abdominal MRI

Pediatr Radiol. 2026 Feb 3. doi: 10.1007/s00247-025-06506-w. Online ahead of print.ABSTRACTBACKGROUND: Fontan-associated liver disease (FALD) is associated with morbidity and mortality in patients with palliated single ventricle congenital heart disease.OBJECTIVE: To develop machine learning models

Hospital-Medicare Advantage Vertical Integration and Cardiopulmonary Care in Integrated Hospitals

JAMA Health Forum. 2025 Dec 5;6(12):e255648. doi: 10.1001/jamahealthforum.2025.5648.ABSTRACTIMPORTANCE: The rate of health care payer and practitioner consolidation is increasing, with limited assessment of hospital-Medicare Advantage (MA) plan vertical integration. Little is known about whether ali

Modulation of inflammasome components in patients with heart failure using oral nutritional supplements: investigating the molecular mechanisms beyond the clinical benefit

No abstractEur J Nutr. 2026 Feb 3;65(2):39. doi: 10.1007/s00394-025-03878-5.NO ABSTRACTPMID:41632188 | DOI:10.1007/s00394-025-03878-5

Safety of Ferric Carboxymaltose in Heart Failure Patients With Iron Deficiency Across Ferritin Levels, Heart Failure Causes, and Prior Hospitalization Status: A Meta-Analysis

No abstractMayo Clin Proc. 2026 Feb 2:S0025-6196(25)19662-6. doi: 10.1016/j.mayocp.2025.12.006. Online ahead of print.NO ABSTRACTPMID:41632068 | DOI:10.1016/j.mayocp.2025.12.006

Computed Tomography Radiomic Signatures Associated With Neutrophil Extracellular Trap Enrichment and First-Pass Outcome in Ischemic Stroke Thrombi

J Am Heart Assoc. 2026 Feb 3:e046619. doi: 10.1161/JAHA.125.046619. Online ahead of print.ABSTRACTBACKGROUND: Radiomic and transcriptomic analyses have independently identified features linked to mechanical thrombectomy (MT) outcomes. Here, we integrated paired radiomics/transcriptomics of stroke cl

Increased Incidence of De Novo Malignancies Compared With Malignancy Recurrences in Survivors of Cancer Undergoing Heart Transplantation

J Am Heart Assoc. 2026 Feb 3:e042779. doi: 10.1161/JAHA.125.042779. Online ahead of print.ABSTRACTBACKGROUND: A proportion of cancer survivors (CS) with heart failure develop advanced heart failure. In select CS with advanced heart failure, heart transplantation (HT) remains the gold standard treatm

Extracellular vesicles for heart repair: origins, functions, bioengineering strategies, and therapeutic potential

J Mater Chem B. 2026 Feb 3. doi: 10.1039/d5tb02080h. Online ahead of print.ABSTRACTHeart disease has become a major threat to global health. In recent years, extracellular vesicles (EVs) have become a research hotspot in heart regeneration and repair due to their unique intercellular communication f

Multimodal imaging in post-infarction pericarditis: Echocardiography versus cardiac magnetic resonance imaging in distinguishing haemorrhagic from inflammatory pericardial complications

No abstractKardiol Pol. 2026 Feb 3. doi: 10.33963/v.phj.110950. Online ahead of print.NO ABSTRACTPMID:41631508 | DOI:10.33963/v.phj.110950

Clinical Features, Management and Outcomes of Supraventricular Tachycardia in Newborns: A 10-Year Multicenter Experience

Acta Paediatr. 2026 Feb 3. doi: 10.1111/apa.70472. Online ahead of print.ABSTRACTAIM: Neonatal supraventricular tachycardia lacks neonatal-specific evidence to guide therapy.METHODS: We retrospectively collected data of neonates with supraventricular tachycardia across two Italian centres between 20

Platelet-Rich Plasma Hydrogel Patch Promotes Hyperacute Cardioprotection after Myocardial Infarction

Tissue Eng Part A. 2026 Feb 3:19373341251412453. doi: 10.1177/19373341251412453. Online ahead of print.ABSTRACTAlternative therapies are needed for heart failure following myocardial infarction (MI), as ischemic cardiomyopathy remains a major global health concern despite advances in acute MI manage

Modulation of Ferroptosis by the Irx3-Etfa Pathway Protects Against Cardiac Hypertrophy

FASEB J. 2026 Feb 15;40(3):e71524. doi: 10.1096/fj.202502033RR.ABSTRACTPathological cardiac hypertrophy is a major contributor to heart failure and is often accompanied by ferroptosis and mitochondrial dysfunction. However, the upstream transcriptional mechanisms governing these processes remain poo

Kinetic and structural characterisation of domain-specific angiotensin I-converting enzyme inhibition by captopril, rentiapril and zofenoprilat

FEBS J. 2026 Feb 3. doi: 10.1111/febs.70428. Online ahead of print.ABSTRACTAngiotensin I-converting enzyme (ACE) is a zinc-dependent dipeptidyl carboxypeptidase involved in blood pressure regulation through proteolysis of angiotensin I (Ang-I) into the potent vasoconstrictor, angiotensin II (Ang-II)

Rosmarinic Acid-Treated Exosomes Modulate TGF-β1/Smad3 Signaling to Alleviate Cardiac Fibrosis in an In Vitro/In Vivo Model

FASEB J. 2026 Feb 15;40(3):e71358. doi: 10.1096/fj.202501842RR.ABSTRACTCardiac fibrosis (CF) is a major complication of myocardial infarction (MI), impairing myocardial function and leading to heart failure. Rosmarinic acid (RA) exhibits cardioprotective and antifibrotic properties, representing a p

Light chain amyloidosis: multidisciplinary management and innovative therapeutic strategies. SIC/ANMCO Consensus document of the Italian Cardiac Amyloidosis Network (RIAC)

G Ital Cardiol (Rome). 2026 Feb;27(2):141-153. doi: 10.1714/4636.46471.ABSTRACTLight chain (AL) amyloidosis is a rare systemic disease caused by monoclonal immunoglobulin light chains with abnormal folding that aggregate into fibrils, which deposit in extracellular tissues. This process leads to cyt

Digital health physical activity coaching for older family caregivers of persons with heart failure - TPA4You: Protocol for a pilot randomized controlled trial

Contemp Clin Trials Commun. 2026 Jan 20;49:101604. doi: 10.1016/j.conctc.2026.101604. eCollection 2026 Feb.ABSTRACTBACKGROUND: Older adult family caregivers of persons with heart failure experience substantial burden due to the complex care needs of their care recipients. Targeted interventions for

Exploring the potential of large language models in healthcare: a focus on cardiovascular disease analysis

Health Inf Sci Syst. 2026 Jan 31;14(1):35. doi: 10.1007/s13755-026-00432-3. eCollection 2026 Dec.ABSTRACTOBJECTIVE: With the rapid development of big data and artificial intelligence technologies, large language models (LLMs) are increasingly being applied across multiple fields. In the healthcare d

Heart failure in pregnancy and postpartum: a nationwide study over 6.3 million of pregnancies in France between 2010 and 2018

AJOG Glob Rep. 2025 Jun 22;5(4):100540. doi: 10.1016/j.xagr.2025.100540. eCollection 2025 Nov.ABSTRACTBACKGROUND: Cardiovascular diseases became the first cause of maternal death in France, but only scarce epidemiological data have been published about heart failure (HF) in pregnancy/postpartum.OBJE

Cardiac resynchronization therapy in chronic Chagas cardiomyopathy: A systematic review and single-arm meta-analysis

Heart Rhythm O2. 2025 Jul 1;6(9):1364-1371. doi: 10.1016/j.hroo.2025.06.018. eCollection 2025 Sep.ABSTRACTBACKGROUND: Cardiac resynchronization therapy (CRT) is a well-established therapy for patients with heart failure. However, patients with chronic Chagas cardiomyopathy (CCC) were underrepresente

Systematic Quality Improvement in Dobutamine Stress Echocardiography: A Two-Cycle Audit Demonstrating Enhanced Diagnostic Accuracy

Cureus. 2026 Jan 2;18(1):e100628. doi: 10.7759/cureus.100628. eCollection 2026 Jan.ABSTRACTBACKGROUND: Dobutamine stress echocardiography (DSE) has become an important and frequently used non-invasive diagnostic tool for assessing significant coronary artery disease (CAD) in clinical practice. This

Diastolic Blood Pressure Variability Predicts Cardiovascular Outcomes in CKD, Especially in Advanced Stages

Kidney Med. 2025 Dec 15;8(2):101219. doi: 10.1016/j.xkme.2025.101219. eCollection 2026 Feb.ABSTRACTRATIONALE & OBJECTIVE: Chronic kidney disease (CKD) is associated with a high risk of cardiovascular events. However, the role of diastolic blood pressure variability (DBPV) in predicting these outcome

Association between genetics variants and clinical outcomes in patients with left ventricular assist device

JHLT Open. 2025 Dec 30;11:100477. doi: 10.1016/j.jhlto.2025.100477. eCollection 2026 Feb.ABSTRACTBACKGROUND: Left ventricular assist device (LVAD) implantation is a life-saving therapy for end-stage heart failure, but right ventricular failure (RVF) remains a major complication. Current RVF risk mod