Mitochondrial translational control in cardiovascular diseases: from mechanisms to therapies

Redox Biol. 2026 Mar 26;92:104143. doi: 10.1016/j.redox.2026.104143. Online ahead of print.ABSTRACTMitochondria orchestrate cardiac metabolic homeostasis, and their dysfunction constitutes a fundamental mechanism driving cardiovascular diseases (CVDs). During eukaryotic evolution, most of the mitoch

Long-Term Durability of Acoramidis Efficacy in Transthyretin Amyloid Cardiomyopathy: Open-Label Extension of the ATTRibute-CM Randomized Clinical Trial

JAMA Cardiol. 2026 Mar 30. doi: 10.1001/jamacardio.2026.0819. Online ahead of print.ABSTRACTIMPORTANCE: Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive disorder caused by destabilization of serum transthyretin (sTTR). Acoramidis, an approved therapy that achieves near-complete (≥90%)

Global Burden of Heart Failure Attributable to Atrial Fibrillation and Flutter, insights from GBD 2021

ESC Heart Fail. 2026 Mar 30:xvag094. doi: 10.1093/eschf/xvag094. Online ahead of print.ABSTRACTAIMS: To systematically quantify the global, regional, and national burden of heart failure (HF) attributable to atrial fibrillation/flutter (AF/AFL) from 1990 to 2021, and project trends to 2040.METHODS A

Group 1 Pulmonary Hypertension With Elevated Pulmonary Artery Wedge Pressure: Characterizing A Complex Phenotype

No abstractCirculation. 2026 Mar 31;153(13):963-966. doi: 10.1161/CIRCULATIONAHA.126.078855. Epub 2026 Mar 30.NO ABSTRACTPMID:41911353 | DOI:10.1161/CIRCULATIONAHA.126.078855

Letter by Meng et al Regarding Article, "An Aberrant Resurgence of Endogenous Retroviruses Prompts Myocarditis and Heart Failure"

No abstractCirculation. 2026 Mar 31;153(13):e1058. doi: 10.1161/CIRCULATIONAHA.125.077923. Epub 2026 Mar 30.NO ABSTRACTPMID:41911350 | DOI:10.1161/CIRCULATIONAHA.125.077923

Response by Xiong and Zhang to Letter Regarding Article, "An Aberrant Resurgence of Endogenous Retroviruses Prompts Myocarditis and Heart Failure"

No abstractCirculation. 2026 Mar 31;153(13):e1059-e1060. doi: 10.1161/CIRCULATIONAHA.125.079058. Epub 2026 Mar 30.NO ABSTRACTPMID:41911347 | DOI:10.1161/CIRCULATIONAHA.125.079058

Adaptive AI for Cardiovascular Event Adjudication: Cardiovascular Event Adjudication Across Different Definitions in the ODYSSEY OUTCOMES and EUCLID Trials

Circulation. 2026 Mar 30. doi: 10.1161/CIRCULATIONAHA.126.080072. Online ahead of print.ABSTRACTBACKGROUND: Clinical endpoint classification (CEC) is the gold standard for cardiovascular endpoint measurement in clinical trials, but adds time and cost. We developed and validated an artificial intelli

Patient-Reported Barriers to Dietary Adherence in Heart Failure: A Qualitative Substudy of the Pro-HEART Trial

Eur J Cardiovasc Nurs. 2026 Mar 30:zvag092. doi: 10.1093/eurjcn/zvag092. Online ahead of print.ABSTRACTAIMS: Dietary interventions can improve outcomes for individuals with heart failure and cardiometabolic comorbidities, yet long-term adherence remains difficult and contributes to high attrition in

Hemangioma congénito rápidamente involutivo, diagnosticado prenatalmente con insuficiencia cardíaca y seguimiento postnatal

Rev Fac Cien Med Univ Nac Cordoba. 2026 Mar 13;83(1):e44679. doi: 10.31053/1853.0605.v83.n1.44679.ABSTRACTDescribir el caso clínico de un RICH que fue diagnosticado intraútero, normalmente en las ecografías obstétricas suelen ser confundidos con malformaciones arteriovenosas y otros tumores congénit

Tanshinone-IIA Mediated Attenuation of Post-Infarction Myocardial Fibrosis via IL-33/ST-2 Signaling Changes in Rat Epicardial Adipose Tissue

J Vis Exp. 2026 Mar 13;(229). doi: 10.3791/70093.ABSTRACTMyocardial infarction (MI), a severe form of coronary artery disease, often results in myocardial fibrosis, a key contributor to cardiac dysfunction and heart failure. Epicardial adipose tissue (EAT) is increasingly implicated in cardiovascula

Intravascular Ultrasound-Guided or Angiography-Guided Complex High-Risk PCI

N Engl J Med. 2026 Mar 30. doi: 10.1056/NEJMoa2601521. Online ahead of print.ABSTRACTBACKGROUND: Intravascular ultrasound (IVUS) guidance during percutaneous coronary intervention (PCI) has been associated with increased stent optimization and reduced adverse events among patients with complex coron

A history that matters: a systematic review and meta-analysis on prior heart failure hospitalization and outcomes after transcatheter aortic valve implantation

No abstractJ Echocardiogr. 2026 Mar 30. doi: 10.1007/s12574-026-00729-y. Online ahead of print.NO ABSTRACTPMID:41910898 | DOI:10.1007/s12574-026-00729-y

Impact of atrial fibrillation catheter ablation on primary prevention ICD eligibility in heart failure with reduced ejection fraction: a systematic review and meta-analysis

No abstractJ Interv Card Electrophysiol. 2026 Mar 30. doi: 10.1007/s10840-026-02302-0. Online ahead of print.NO ABSTRACTPMID:41910893 | DOI:10.1007/s10840-026-02302-0

Predicting sudden cardiac death in heart failure with reduced ejection fraction

No abstractHeart Fail Rev. 2026 Mar 30;31(1):50. doi: 10.1007/s10741-026-10619-1.NO ABSTRACTPMID:41910831 | DOI:10.1007/s10741-026-10619-1

Multiscale computational modeling of the cardiopulmonary consequences of postnatal hyperoxia with implications for preterm-born children

Biomech Model Mechanobiol. 2026 Mar 30;25(2):32. doi: 10.1007/s10237-026-02047-9.ABSTRACTModerate to extreme preterm birth (< 32 weeks gestation) affects cardiopulmonary structure and function and is associated with increased risk of heart failure through adulthood. The rat hyperoxia (Hx) model (ter

You evaluation of the PARACHUTE-HF trial: role of sacubitril/valsartan compared to enalapril on outcomes in patients with heart failure from Chagas' disease

No abstractHeart Fail Rev. 2026 Mar 30;31(1):49. doi: 10.1007/s10741-026-10617-3.NO ABSTRACTPMID:41910669 | DOI:10.1007/s10741-026-10617-3

Cardiac contractility modulation in heart failure management: unraveling molecular mechanisms to improve patient selection in heart failure management

No abstractHeart Fail Rev. 2026 Mar 30;31(1):48. doi: 10.1007/s10741-026-10610-w.NO ABSTRACTPMID:41910667 | DOI:10.1007/s10741-026-10610-w

Association of GLP-1 Receptor Agonists Versus Bariatric Surgery with Outcomes in Obese Patients with Hypertrophic Cardiomyopathy: A Multicenter Propensity-Matched Analysis

Eur Heart J Qual Care Clin Outcomes. 2026 Mar 30:qcag051. doi: 10.1093/ehjqcco/qcag051. Online ahead of print.ABSTRACTBACKGROUND: Obesity is linked with worse outcomes in hypertrophic cardiomyopathy (HCM). While both bariatric surgery (BS) and GLP-1 receptor agonists (GLP-1RA) promote weight loss an

CMR-derived skeletal muscle T1 time and extracellular volume as novel diagnostic markers for cardiac amyloidosis

Eur J Clin Invest. 2026 Apr;56(4):e70191. doi: 10.1111/eci.70191.ABSTRACTINTRODUCTION: Cardiac amyloidosis (CA) is a progressive cardiomyopathy caused by amyloid deposition, leading to heart failure and increased mortality. Cardiac magnetic resonance (CMR) identifies myocardial involvement via eleva

Excess and Dysfunctional Fat as a Primary Driver of Heart Failure With Preserved Ejection Fraction: From Institutional Recognition to Clinical Integration

JACC Heart Fail. 2026 Mar 29:103046. doi: 10.1016/j.jchf.2026.103046. Online ahead of print.ABSTRACTEpidemiological and Mendelian randomization studies demonstrate a strong link between central obesity, visceral adiposity, and heart failure with preserved ejection fraction (HFpEF). The AHA (American

Reclassification of Diastolic Function by the 2025 American Society of Echocardiography Diastolic Function Guidelines and Risk of Mortality

J Am Soc Echocardiogr. 2026 Mar 30:S0894-7317(26)00037-4. doi: 10.1016/j.echo.2026.01.006. Online ahead of print.ABSTRACTBACKGROUND: Whether the 2025 American Society of Echocardiography (ASE) diastolic dysfunction (DD) algorithm (DD25) improves mortality prognostication compared to the 2016 algorit

Impact of Left Ventricular Geometry on All-Cause Mortality in Patients Undergoing Hemodialysis: A Longitudinal Observational Study

Kidney360. 2026 Mar 1;7(3):602-612. doi: 10.34067/KID.0000000963. Epub 2025 Oct 29.ABSTRACTKEY POINTS: We evaluated the association between the four categories of left ventricular geometry and all-cause mortality in patients undergoing hemodialysis. Concentric hypertrophy was the most prevalent, fol

Discontinuation of Beta-Blocker Therapy after Myocardial Infarction

N Engl J Med. 2026 Mar 30. doi: 10.1056/NEJMoa2601005. Online ahead of print.ABSTRACTBACKGROUND: The role of long-term beta-blocker therapy after a myocardial infarction in patients without left ventricular systolic dysfunction or heart failure is unclear in the era of contemporary coronary-artery r

Optimal treatment choices for adult atrial septal defects: the role of appropriate risk stratification

Expert Rev Cardiovasc Ther. 2026 Mar 30. doi: 10.1080/14779072.2026.2653712. Online ahead of print.ABSTRACTINTRODUCTION: Adult atrial septal defect (ASD) is no longer regarded as a benign congenital lesion, as long-term follow-up studies have demonstrated substantial risks of atrial arrhythmias, hea