Interventional treatment options for elderly patients with mitral regurgitation

Future Cardiol. 2026 Aug 17:1-6. doi: 10.1080/14796678.2026.2718644. Online ahead of print.ABSTRACTThe prevalence of mitral regurgitation (MR), particularly degenerative MR (DMR), rises with advancing age. Elderly patients frequently carry increased surgical risk due to frailty and comorbidities, le

Complete Heart Block Unmasking Transthyretin Cardiac Amyloidosis: A Multimodality Imaging Case Report

Cureus. 2026 Jul 17;18(7):e112834. doi: 10.7759/cureus.112834. eCollection 2026 Jul.ABSTRACTTransthyretin cardiac amyloidosis (ATTR-CM) is an increasingly recognized infiltrative cardiomyopathy characterized by progressive myocardial amyloid deposition, leading to heart failure, arrhythmias, and con

Coinfection With Nocardia exalbida and Mycobacterium tuberculosis Following Steroid Pulse Therapy: A Case Report and Literature Review

Cureus. 2026 Jul 17;18(7):e112843. doi: 10.7759/cureus.112843. eCollection 2026 Jul.ABSTRACTWe report a case of pulmonary nocardiosis and pulmonary tuberculosis following steroid pulse therapy for presumed myelitis. A 74-year-old man with transthyretin amyloid cardiomyopathy, chronic heart failure,

Transformative Approaches to Biomarker Assessment and Clinical Profiles in Pulmonary Hypertension Patients : Short title: Biomarker Assessment and Clinical Profiles in Pulmonary Hypertension Patients

Galen Med J. 2025 Dec 18;15:e4132. doi: 10.31661/gmj.vi.4132. eCollection 2026.ABSTRACTBACKGROUND: Pulmonary hypertension (PH) is a progressive disorder marked by elevated pulmonary arterial pressure, leading to right heart failure and high mortality. Emerging evidence links metabolic disturbances,

Management of Recurrent Atrial Fibrillation After Catheter Ablation: Five-Year Outcomes of Repeat Catheter Ablation Versus Antiarrhythmic Therapy

Europace. 2026 Aug 17:euag215. doi: 10.1093/europace/euag215. Online ahead of print.ABSTRACTBACKGROUND: Recurrence of symptomatic atrial fibrillation (AF) after catheter ablation (CA) is not uncommon. However, real-world long-term data on clinical outcomes of rhythm control strategies in patients wi

Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy

Cardiovasc Res. 2026 Aug 17:cvag175. doi: 10.1093/cvr/cvag175. Online ahead of print.ABSTRACTAIMS: Free fatty acid receptor 4 (Ffar4) is a receptor for long-chain fatty acids that attenuates heart failure driven by increased afterload. Recent findings suggest that Ffar4 prevents ischemic injury in b

Hemodynamic characterization of cardiac dysfunction after traumatic brain injury using a controlled cortical impact model in male rats

Physiol Rep. 2026 Aug;14(16):e71055. doi: 10.14814/phy2.71055.ABSTRACTTraumatic brain injury (TBI) is associated with cardiovascular dysfunction that worsens clinical outcomes, yet the underlying mechanisms are poorly understood. Clinical studies are limited by heterogeneity, highlighting the need f

A Rare Presentation of Behçet's Disease: Coexistence of Intracardiac Thrombi, Coronary Artery Disease, and Pulmonary Thromboembolism

Catheter Cardiovasc Interv. 2026 Aug 16. doi: 10.1002/ccd.70828. Online ahead of print.ABSTRACTBehçet's disease (BD) is a rare systemic vasculitis. While pulmonary involvement occurs, severe intracardiac manifestations are exceptional. We report a 44-year-old male presenting with dyspnea and hemopty

Curcumin-Preconditioned Adipose-Derived Stem Cells Improve Cardiac Function in Aged Rats via miR-3575 Modulation

Stem Cells Dev. 2026 Aug 16:15473287261474670. doi: 10.1177/15473287261474670. Online ahead of print.ABSTRACTAging causes a decrease in cardiac function in living organisms. Although stem cell transplantation shows therapeutic potential for aging hearts, distinct types of evidence have indicated tha

Stem Cell-Derived Mitochondria-Enriched Preservation Solutions as Organelle-Based Therapeutic Strategy for Cold Storage of Liver and Kidney

Adv Healthc Mater. 2026 Aug 16:e71510. doi: 10.1002/adhm.71510. Online ahead of print.ABSTRACTOrgan preservation remains a critical challenge in transplantation, primarily due to hypothermia-induced oxidative stress and metabolic dysfunction. Here, we report a mitochondria-enriched, cell-free preser

Laxative Selection in Constipated Patients With Heart Failure: Clinical Considerations, Safety Concerns, and Current Evidence

No abstractAm J Med Sci. 2026 Aug 16:S0002-9629(26)00314-9. doi: 10.1016/j.amjms.2026.08.004. Online ahead of print.NO ABSTRACTPMID:42604687 | DOI:10.1016/j.amjms.2026.08.004

Acute myocardial infarction complicated by interventricular septal rupture and left ventricular thrombus

Medicina (B Aires). 2026;86(4):1050-1054.ABSTRACTWe present the case of a 76-year-old woman, with a history of smoking and dyslipidemia, who was admitted with acute heart failure associated with a holosystolic murmur. The electrocardiogram showed an anterior ST-segment elevation myocardial infarctio

Intracavitary thrombus as a differential diagnosis of intramyocardial dissection

Medicina (B Aires). 2026;86(4):1040-1043.ABSTRACTWe present the case of a 47-year-old man with ischemic cardiomyopathy and a previous extensive acute myocardial infarction (AMI), who had undergone multiple percutaneous coronary interventions and progressed to advanced heart failure. During evaluatio

The Impact of Hospital Infrastructure Investment on Quality of Care

Med Care Res Rev. 2026 Aug 16:10775587261471942. doi: 10.1177/10775587261471942. Online ahead of print.ABSTRACTHospitals spend billions of dollars annually on major construction projects and facility upgrades, but limited research to date has examined whether this expenditure benefits patients. Usin

Validation of the Arabic Version of Patient Health Questionnaire-9 in Omani and Yemeni Patients With Chronic Physical Diseases

Int J Methods Psychiatr Res. 2026 Sep;35(3):e70100. doi: 10.1002/mpr.70100.ABSTRACTBACKGROUND: Secondary depression frequently develops in people with chronic diseases, and it may hinder disease progress and treatment outcomes. This study aimed to examine the construct validity and measurement invar

Contemporary outcomes of the Fontan operation: An Australian and New Zealand Fontan Registry study

JTCVS Open. 2026 May 4;32:101833. doi: 10.1016/j.xjon.2026.101833. eCollection 2026 Aug.ABSTRACTOBJECTIVE: We sought to review the impact of extracardiac conduit size and risk factors on the long-term outcomes of the contemporary Fontan procedure: lateral tunnel and extracardiac conduits.METHODS: Da

Survival and outcomes of coronary artery bypass grafting in patients with extremely low ejection fraction (≤20%): A systematic review and meta-analysis

JTCVS Open. 2026 Jun 6;32:101922. doi: 10.1016/j.xjon.2026.101922. eCollection 2026 Aug.ABSTRACTOBJECTIVES: To assess perioperative outcomes and long-term survival of coronary artery bypass in patients with ejection fraction (EF) 20% or less.METHODS: We performed a systematic search of MEDLINE, EMBA

Mitigating conduction disturbances in sutureless aortic valve surgery: A standardized anti-oversizing strategy in a large single-center program

JTCVS Open. 2026 May 2;32:101822. doi: 10.1016/j.xjon.2026.101822. eCollection 2026 Aug.ABSTRACTOBJECTIVES: The study objectives were to characterize conduction outcomes and perioperative results in a large, consecutive, single-center program of sutureless self-expanding aortic bioprosthesis implant

Heart transplantation outcomes in patients with Fontan circulation: Updated systematic review and meta-analysis

JTCVS Open. 2026 May 7;32:101855. doi: 10.1016/j.xjon.2026.101855. eCollection 2026 Aug.ABSTRACTOBJECTIVE: A subset of patients with Fontan circulation develops progressive circulatory failure requiring advanced therapies such as heart transplantation. We performed an updated systematic review and m

Outcomes of surgical and transcatheter aortic valve replacement in patients with large and extra-large aortic annuli

JTCVS Open. 2026 May 8;32:101856. doi: 10.1016/j.xjon.2026.101856. eCollection 2026 Aug.ABSTRACTOBJECTIVE: The study objective was to evaluate outcomes after aortic valve replacement in patients with large or extra-large annuli.METHODS: We conducted a retrospective cohort study of adults undergoing

From Carcinoid Syndrome to Carcinoid Heart Disease: The Cost of Delayed Cardiac Surveillance

Cureus. 2026 Jul 16;18(7):e112770. doi: 10.7759/cureus.112770. eCollection 2026 Jul.ABSTRACTCarcinoid heart disease (CHD) is a serious cardiac manifestation of carcinoid syndrome (CS), characterized by progressive fibrotic degeneration of cardiac valves and right-sided heart failure. We report the c

Paying the toll: Transfusion and outcomes of patients bridged with mechanical circulatory support to heart transplantation

JTCVS Open. 2026 May 2;32:101851. doi: 10.1016/j.xjon.2026.101851. eCollection 2026 Aug.ABSTRACTOBJECTIVE: Various mechanical circulatory support (MCS) strategies exist to bridge patients with heart failure to heart transplant. This study provides a comprehensive analysis comparing perioperative tra

Machine learning prediction of right heart failure after left ventricular assist device implantation with individual risk factor visualization

JTCVS Open. 2026 Mar 19;32:101728. doi: 10.1016/j.xjon.2026.101728. eCollection 2026 Aug.ABSTRACTBACKGROUND: Right ventricular failure (RVF) is a major adverse event after left ventricular assist device (LVAD) implantation, but its complex mechanisms make accurate prediction challenging. While super

Ninety-day venous thromboembolism incidence and associated risk factors after total and reverse shoulder arthroplasty: a national database analysis

J Shoulder Elb Arthroplast. 2026 Jul 15;10(4):100061. doi: 10.1016/j.jsea.2026.100061. eCollection 2026 Dec.ABSTRACTBACKGROUND: Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is an uncommon but potentially serious complication following total shoulder arthroplas