Longitudinal associations of cumulative and repeated-measure patterns of insulin resistance surrogate indices with biological age acceleration and incident cardiovascular disease across cardiovascular-kidney-metabolic syndrome stages 0-3: evidence from CHARLS 2011-2020

Cardiovasc Diabetol. 2026 May 16. doi: 10.1186/s12933-026-03206-z. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome stages 0-3 represent a critical window for preventing progression to overt cardiovascular disease (CVD). Insulin resistance (IR) is central to C

Predictors of metabolic syndrome among type II diabetic patients visiting public hospitals in Sidama Region, Ethiopia: unmatched case control study

BMC Cardiovasc Disord. 2026 May 16. doi: 10.1186/s12872-026-05982-8. Online ahead of print.ABSTRACTINTRODUCTION: Metabolic syndrome (MetS) is a series of health conditions, including insulin resistance, abdominal obesity, hypertension, and dyslipidemia. In diabetic patients, MetS elevates the risks

Ambulatory venoarterial ECMO via right subclavian artery and internal jugular vein cannulation: a novel technical approach to bridge-to-transplant

J Artif Organs. 2026 May 16;29(2):31. doi: 10.1007/s10047-026-01555-w.ABSTRACTStandard femoral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) severely limits patient mobility. We introduce a novel "femoral-free" Ambulatory Subclavian-Jugular V-A ECMO technique to maximize rehabilitatio

Sudden cardiac death and major arrhythmic events in patients with Fabry disease: risk stratification in the FHFc multicenter study

Heart Rhythm. 2026 May 15:S1547-5271(26)02388-X. doi: 10.1016/j.hrthm.2026.05.021. Online ahead of print.ABSTRACTBACKGROUND: Fabry disease (FD) is a rare X-linked genetic disorder due to alpha-galactosidase deficiency. Cardiovascular complications, including ventricular arrhythmias and conduction ab

Globotriaosylceramide (Gb3) implications in cardiovascular disease for its mechanistic insights, food chemistry aspects and clinical significance - A review

Int J Biol Macromol. 2026 May 15:152557. doi: 10.1016/j.ijbiomac.2026.152557. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a major non-communicable disease that can be influenced by the accumulation of Globotriaosylceramide (Gb3), a glycosphingolipid associated with circulating lipo

Design and Rationale of the WE-CARE-HF-CMR Trial: Cardiorenal Care on Wheels for Asymptomatic Heart Failure Patients (NCT07185100)

J Cardiovasc Magn Reson. 2026 May 15:102745. doi: 10.1016/j.jocmr.2026.102745. Online ahead of print.ABSTRACTBACKGROUND: Heart failure (HF) is a significant public health concern. Early detection, particularly during the asymptomatic stage, is essential for prompt intervention and preventing progres

Vascular and musculoskeletal interactions: structure, function, and therapeutic strategies for sarcopenia and osteoporosis

MedScience. 2026 May 16. doi: 10.1007/s11684-026-1204-4. Online ahead of print.ABSTRACTMuscle and bone, key tissues that maintain the body's structure and function, are closely connected via mechanical and biochemical interactions. The vascular system plays a crucial role in musculoskeletal health,

Highlights of Cardiovascular Disease Prevention Studies Presented at the 2026 American College of Cardiology Conference

Curr Atheroscler Rep. 2026 May 16;28(1):49. doi: 10.1007/s11883-026-01424-0.ABSTRACTPURPOSE OF REVIEW: To summarize key findings from cardiovascular disease prevention trials at the 2026 American College of Cardiology (ACC) Conference.RECENT FINDINGS: The Ez-PAVE trial demonstrated that targeting lo

Association of Hypertension With Health Care Access and Utilization Following Childbirth: Differences by Race and Ethnicity

JACC Adv. 2026 May 4:102778. doi: 10.1016/j.jacadv.2026.102778. Online ahead of print.ABSTRACTBACKGROUND: Hypertensive disorders of pregnancy raise long-term cardiovascular risk, but little is known about health care access and preventive utilization in the years postpartum.OBJECTIVES: The objective

Lost in Transition: Postpartum Care Discontinuity and Cardiovascular Risk After Hypertensive Pregnancy

No abstractJACC Adv. 2026 May 15:102779. doi: 10.1016/j.jacadv.2026.102779. Online ahead of print.NO ABSTRACTPMID:42142106 | DOI:10.1016/j.jacadv.2026.102779

Defecation Patterns and Cardiovascular Outcomes in Acute Coronary Syndrome: The Influence of Stimulant Laxative Use

JACC Asia. 2026 May 11:S2772-3747(26)00116-X. doi: 10.1016/j.jacasi.2026.01.035. Online ahead of print.ABSTRACTBACKGROUND: Appropriate defecation patterns may be important for the prevention of recurrent cardiovascular events.OBJECTIVES: This study aimed to investigate the association of defecation

Dual-trajectories of Systolic Blood Pressure and Modified Life's Essential 8 With Gastrointestinal Cancer and All-Cause Mortality: A Prospective Cohort Study

J Clin Hypertens (Greenwich). 2026 May;28(5):e70292. doi: 10.1111/jch.70292.ABSTRACTThis study aimed to describe joint longitudinal patterns of SBP and modified Life's Essential 8 (LE8) and to further investigate their associations with risks of gastrointestinal cancer and all-cause mortality in the

Should Aspirin Be Discontinued in Patients Taking It for Primary Cardiovascular Prevention?

No abstractJ Am Geriatr Soc. 2026 May 16. doi: 10.1111/jgs.70512. Online ahead of print.NO ABSTRACTPMID:42142004 | DOI:10.1111/jgs.70512

Influenza vaccination attenuates acute myocardial infarction and stroke risk following influenza infection: a register-based, self-controlled case series study, Denmark, 2014 to 2025

Euro Surveill. 2026 Apr;31(13):2500706. doi: 10.2807/1560-7917.ES.2026.31.13.2500706.ABSTRACTBACKGROUNDInfluenza infection is a recognised trigger of acute myocardial infarction (AMI) and stroke, but whether influenza vaccination modifies this risk remains unclear.AIMWe aimed to quantify the short-t

Delayed cardiogenic shock following spontaneous coronary artery dissection in a young, healthy female: a case report

J Med Case Rep. 2026 May 15. doi: 10.1186/s13256-026-06072-1. Online ahead of print.ABSTRACTBACKGROUND: Spontaneous coronary artery dissection (SCAD) is a rare, non-atherosclerotic cause of acute coronary syndrome that predominantly affects young, healthy women without conventional cardiovascular ri

Risk prediction and prevention in patients with advanced subclinical atherosclerosis

BMC Cardiovasc Disord. 2026 May 15. doi: 10.1186/s12872-026-05968-6. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular diseases (CVD) continue to be the leading cause of global mortality. Despite the alarming statistics, effective prevention of CVD remains a significant challenge in practice.

Comparative effectiveness of transitional care interventions for hospital-to-home transition in heart failure: an updated systematic review and network meta-analysis

BMC Cardiovasc Disord. 2026 May 15. doi: 10.1186/s12872-026-05929-z. Online ahead of print.ABSTRACTBACKGROUND: The transition from hospital to home represents a high-risk "vulnerable period" for patients with heart failure (HF). While numerous transitional care interventions (TCIs) have been develop

Simvastatin rescues cognitive impairment in an Aβ1-42-induced model of Alzheimer's disease through the HDAC2-BDNF signaling pathway

Neuropsychopharmacology. 2026 May 15. doi: 10.1038/s41386-026-02440-z. Online ahead of print.ABSTRACTStatins, renowned for their efficacy in treating cardiovascular diseases, have emerged as potential therapeutic agents for the prevention of Alzheimer's disease (AD). Among them, simvastatin (SV) has

Associations of preconception retinal microvasculature with lipid profiles from mid-pregnancy to three months postpartum

NPJ Cardiovasc Health. 2026 May 15. doi: 10.1038/s44325-026-00130-9. Online ahead of print.ABSTRACTWe examined associations between preconception retinal microvasculature and maternal dyslipidemia at mid-pregnancy and three months postpartum in 366 women (mean age 29.9 years). Preconception retinal

Correlation between the modified cardiometabolic index and the incidence of cardiovascular disease in a population with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study

Sci Rep. 2026 May 15. doi: 10.1038/s41598-026-49385-3. Online ahead of print.ABSTRACTThe global burden of cardiovascular disease (CVD) is substantial, particularly among individuals with cardiovascular-kidney-metabolic (CKM) syndrome. This study aimed to examine the relationship between the modified

HDL and coronary artery disease

No abstractJ Clin Lipidol. 2026 Apr 30:S1933-2874(26)00130-3. doi: 10.1016/j.jacl.2026.04.024. Online ahead of print.NO ABSTRACTPMID:42140833 | DOI:10.1016/j.jacl.2026.04.024

Risk factors for atrial fibrillation in Ibadan, Nigeria: A case-controlled study

J Natl Med Assoc. 2026 May 15:S0027-9684(26)00063-5. doi: 10.1016/j.jnma.2026.03.013. Online ahead of print.ABSTRACTBACKGROUND: Atrial fibrillation (AF) is a common arrhythmia that is a potent independent risk factor for stroke. The incidence of AF increases with age, and most affected people have u

Bidirectional association between breast cancer and cardiovascular disease: Longitudinal analysis of UK Biobank data

Atherosclerosis. 2026 May;416:120662. doi: 10.1016/j.atherosclerosis.2026.120662. Epub 2026 May 14.ABSTRACTBACKGROUND AND AIMS: Breast cancer (BC) and cardiovascular disease (CVD) are leading causes of death in women. However, their bidirectional relationship and key risk factors remain unclear.METH

The aorta in Marfan syndrome - from molecular mechanisms to mechanobiological dysfunction

Cardiovasc Res. 2026 May 15:cvag114. doi: 10.1093/cvr/cvag114. Online ahead of print.ABSTRACTMarfan syndrome (MFS) is an autosomal dominant connective tissue disorder that affects cardiovascular, musculoskeletal, and ocular tissues, with premature death often resulting from dissection of the thoraci