The relative importance of neighborhood environment features in explaining preeclampsia risk using machine learning

Pregnancy (Hoboken). 2026 Sep 29;2(6):e70347. doi: 10.1002/pmf2.70347. eCollection 2026 Nov.ABSTRACTINTRODUCTION: Disentangling the role of the neighborhood environment in preeclampsia pathogenesis is crucial for addressing social and structural determinants of pregnancy health. Building on epidemio

Predicted 10-year cardiometabolic risk among hospital staff: a cross-sectional study

Front Public Health. 2026 Sep 16;14:1929290. doi: 10.3389/fpubh.2026.1929290. eCollection 2026.ABSTRACTOBJECTIVE: Chronic diseases and cardiometabolic disorders are major public health and occupational health challenges in Taiwan, particularly among healthcare workers exposed to shift work, high occ

Lipoprotein(a) levels and estimated QRISK3 cardiovascular risk in the Randox Health 2025 cohort: a cross-sectional analysis of 14,848 individuals

Front Cardiovasc Med. 2026 Sep 16;13:1949855. doi: 10.3389/fcvm.2026.1949855. eCollection 2026.ABSTRACTINTRODUCTION: Lipoprotein(a) (Lp(a)) is an independent, genetically-determined cardiovascular risk factor not currently incorporated into standard cardiovascular risk prediction models such as QRIS

Cross-Sectional and Longitudinal Associations Between Dietary Intake and Depressive Symptoms in Young South African Adults: The African-PREDICT Study

Depress Anxiety. 2026 Sep 29;2026:2938819. doi: 10.1155/da/2938819. eCollection 2026.ABSTRACTINTRODUCTION: Depression is highly prevalent among young adults worldwide. While research links health behaviours, such as dietary intake, to depression, few studies have examined these associations in low-

Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study

medRxiv [Preprint]. 2026 Sep 7:2026.09.01.26361997. doi: 10.64898/2026.09.01.26361997.ABSTRACTBACKGROUND: The effect of neurovascular health on cardiovascular outcomes is not well-known. Cerebral small vessel disease (CSVD) signals subclinical vascular brain injury and its quantification may serve a

Prediction of Type 2 Diabetes using genomics and proteomics: the HUNT Study (ProtRS for T2D)

medRxiv [Preprint]. 2026 Sep 8:2026.09.06.26362374. doi: 10.64898/2026.09.06.26362374.ABSTRACTType 2 diabetes (T2D) is a multifactorial metabolic disorder with an increasing global prevalence and significant health burdens. Early identification of individuals at high risk is crucial for timely inter

Updated Meta-Analysis of Left Atrial Appendage Closure Versus Oral Anticoagulation to Prevent Stroke in Atrial Fibrillation

Stroke. 2026 Oct 1. doi: 10.1161/STROKEAHA.126.057089. Online ahead of print.ABSTRACTBACKGROUND: Ninety percent of left atrial thrombi in nonvalvular atrial fibrillation arise in the left atrial appendage, which can be occluded percutaneously (left atrial appendage closure [LAAC]). Two 2026 trials (

Acetyltransferase MOF Regulates Macrophage Inflammation in Abdominal Aortic Aneurysms

Circ Res. 2026 Oct 1. doi: 10.1161/CIRCRESAHA.126.329212. Online ahead of print.ABSTRACTBACKGROUND: Abdominal aortic aneurysms (AAAs) are a life-threatening cardiovascular disease for which there is a lack of therapy preventing aortic rupture. During AAA formation, pathological vascular remodeling i

Hypermetabolic State Drives Platelet Dysfunction in Human and Mouse Metabolic Dysfunction-Associated Steatotic Liver Disease

Arterioscler Thromb Vasc Biol. 2026 Oct 1. doi: 10.1161/ATVBAHA.126.325001. Online ahead of print.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing health concern given rising global prevalence, limited diagnostic and therapeutic tools, and strong asso

Pharmacological treatment strategies to prevent heart failure across the cardiovascular-kidney-metabolic spectrum: an EJHF Expert Consensus Statement

Eur J Heart Fail. 2026 Oct 1:xuag301. doi: 10.1093/ejhf/xuag301. Online ahead of print.ABSTRACTHeart failure (HF) remains a major cause of morbidity, mortality, and increased healthcare costs worldwide, and is recognized as the result of progressive cardiovascular-kidney-metabolic (CKM) syndrome. Ob

Fibroblast Growth Factor 2 Enhances Contraction of Arterioles in the Medulla Oblongata and the Basilar Artery in Mice With Chronic Kidney Disease

Acta Physiol (Oxf). 2026 Nov;242(11):e70327. doi: 10.1111/apha.70327.ABSTRACTAIM: Chronic kidney disease (CKD) augments vascular contractility in multiple vascular beds. Fibroblast growth factor 2 (FGF2), whose expression is upregulated in CKD, acts pro-contractile by supporting vasoconstrictor capa

Young Mice Exhibit Increased Relative Ventricular Remodeling After AMI-A Longitudinal CMR Study

Aging Cell. 2026 Oct;25(10):e70748. doi: 10.1111/acel.70748.ABSTRACTCardiovascular diseases are the leading cause of mortality worldwide, with myocardial infarction (MI) contributing significantly to this burden. While age-related differences in cardiac remodeling and healing post MI are well-docume

Chronic Hypertension and Cardiovascular Disease After Preeclampsia: A Danish Nationwide Register-Based Cohort Study Identifying Women at High Risk

Eur J Prev Cardiol. 2026 Oct 1:zwag507. doi: 10.1093/eurjpc/zwag507. Online ahead of print.ABSTRACTAIMS: Preeclampsia is associated with future cardiovascular disease (CVD), yet systematic approaches to identify those requiring intensified prevention are lacking. We aimed to characterise these women

Antithrombotic Therapy in Patients with Chronic Coronary Disease on Anticoagulation: Evidence from Contemporary Trials

Curr Vasc Pharmacol. 2026 Sep 29. doi: 10.2174/0115701611491082260918125921. Online ahead of print.ABSTRACTINTRODUCTION: Chronic coronary disease (CCD) commonly coexists with long-term oral anticoagulation (OAC), particularly for atrial fibrillation (AF). Combination antiplatelet therapy increases b

Religious order membership and cognitive function: Evidence for slower late-life decline despite higher incident dementia

J Alzheimers Dis. 2026 Sep 30:13872877261490593. doi: 10.1177/13872877261490593. Online ahead of print.ABSTRACTBackgroundSocial context influences cognitive aging, yet it is unknown whether highly structured living environments characterized by consistent routines, shared roles, and stable daily act

Body Roundness Index Trajectories and Incident Left Ventricular Hypertrophy: Results of a Community-Based Study in Korea

Echocardiography. 2026 Oct;43(10):e70644. doi: 10.1111/echo.70644.ABSTRACTBACKGROUND: Left ventricular hypertrophy (LVH) constitutes Stage B heart failure and marks elevated risk for atrial fibrillation, stroke, and death. Unlike body mass index, body roundness index (BRI), derived from waist circum

Dysphagia and Oral Health in Older Adults: Examining Demographic and Clinical Associations

Dysphagia. 2026 Oct 1. doi: 10.1007/s00455-026-11007-5. Online ahead of print.ABSTRACTOral health is a modifiable risk factor with significant implications for general health, particularly in the geriatric patient population. Poor oral hygiene has been linked to respiratory disease, aspiration pneum

Plasma Proteomic Signatures for Early Risk Stratification Across Cardiovascular-Kidney-Metabolic Stages 0-2

Diabetes Obes Metab. 2026 Sep 30. doi: 10.1111/dom.71399. Online ahead of print.ABSTRACTAIMS: Cardiovascular-kidney-metabolic (CKM) stages 0-2 represent a potentially modifiable period before overt cardiovascular complications, yet molecular markers that identify individuals at higher downstream ris

Intramuscular Fat as a Biomarker of Muscle Health: Strengths, Limitations and Open Challenges

J Cachexia Sarcopenia Muscle. 2026;17(5):e70389. doi: 10.1002/jcsm.70389.ABSTRACTIntramuscular fat (IMF), also known as myosteatosis, refers to the accumulation of lipids within and around skeletal muscle fibres. Excess IMF is increasingly recognised as a sign of poor muscle quality, linked to reduc

Association of Cardiometabolic Index With Cardiometabolic Disease Prevalence and Mortality: Evidence From Two National Surveys

Heart Lung Circ. 2026 Sep 30:S1443-9506(26)00419-1. doi: 10.1016/j.hlc.2026.05.012. Online ahead of print.ABSTRACTBACKGROUND: The cardiometabolic index (CMI), a composite marker derived from the product of waist-to-height ratio and triglyceride-to- high-density lipoprotein cholesterol ratio, has eme

Estimated small dense low-density lipoprotein cholesterol in predicting atherosclerotic cardiovascular disease: Longitudinal evidence from over 1 million Japanese adults

J Clin Lipidol. 2026 Sep 15:S1933-2874(26)00514-3. doi: 10.1016/j.jacl.2026.09.005. Online ahead of print.ABSTRACTBACKGROUND: Small dense low-density lipoprotein cholesterol (sdLDL-C) is an atherogenic LDL-C subfraction associated with atherosclerotic cardiovascular disease (ASCVD). Although sdLDL-C

Performing lifestyle changes and reducing stroke risk: a process evaluation of a stroke prevention intervention

BMJ Open. 2026 Sep 30;16(9):e123012. doi: 10.1136/bmjopen-2026-123012.ABSTRACTOBJECTIVE: To examine the implementation process, mechanisms of change and contextual influences of a stroke prevention intervention.DESIGN: A process evaluation following the UK Medical Research Council's process evaluati

Can we optimize the efficacy of aspirin for cardiovascular prevention?

No abstractJ Thromb Haemost. 2026 Oct;24(10):3455-3457. doi: 10.1016/j.jtha.2026.07.011.NO ABSTRACTPMID:42816013 | DOI:10.1016/j.jtha.2026.07.011

Cardio-metabolic biomarkers including circulating ketone bodies and risk of incident atrial fibrillation in the multi-ethnic study of atherosclerosis (MESA)

Prog Cardiovasc Dis. 2026 Sep 30:S0033-0620(26)00109-X. doi: 10.1016/j.pcad.2026.09.010. Online ahead of print.ABSTRACTBACKGROUND: Atrial fibrillation (AF) reflects systemic cardio-metabolic dysfunction. While myocardial stress and injury biomarkers are associated with incident AF, the role of keton