Deconditioning in coronary artery disease: an underrecognized problem with contemporary clinical relevance

Coron Artery Dis. 2026 Aug 17. doi: 10.1097/MCA.0000000000001667. Online ahead of print.ABSTRACTCoronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide. Beyond recurrent ischemic events, many patients experience a sustained and gradual reduction in physical activit

National Impact of 2026 ACC/AHA PREVENT-ASCVD Risk Thresholds on Statin Eligibility in U.S. Adults

No abstractDiabetes Obes Metab. 2026 Aug 17. doi: 10.1111/dom.71228. Online ahead of print.NO ABSTRACTPMID:42605544 | DOI:10.1111/dom.71228

Germline predisposition and somatic mutational landscape in synchronous mucinous metaplasia and neoplasia of the female genital tract

Clin Transl Med. 2026 Aug;16(8):e70768. doi: 10.1002/ctm2.70768.ABSTRACTBACKGROUND: Synchronous mucinous metaplasia and neoplasia of the female genital tract (SMMN-FGT) with gastric-type differentiation is a rare disorder with genetic predisposition. Pathogenic STK11 variants explain only a minority

Assessing the prognostic value of artificial intelligence for opportunistic prediction of coronary artery calcium score on routine non-gated computed tomography in patients treated with immune checkpoint inhibitors

Digit Health. 2026 Aug 14;12:20552076261480207. doi: 10.1177/20552076261480207. eCollection 2026 Jan-Dec.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICI) improve cancer outcomes but are associated with increased atherosclerotic cardiovascular risk. Opportunistic coronary artery calcium (CAC) a

Negotiating body self-concept in Iranian women living with obesity: A qualitative phenomenological study

Health Psychol Open. 2026 Aug 14;13:20551029261477150. doi: 10.1177/20551029261477150. eCollection 2026 Jan-Dec.ABSTRACTBackground: Body self-concept is vital to psychological well-being, yet little is known about how women living with obesity in non-Western contexts, particularly Iran, negotiate th

Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy

Cardiovasc Res. 2026 Aug 17:cvag175. doi: 10.1093/cvr/cvag175. Online ahead of print.ABSTRACTAIMS: Free fatty acid receptor 4 (Ffar4) is a receptor for long-chain fatty acids that attenuates heart failure driven by increased afterload. Recent findings suggest that Ffar4 prevents ischemic injury in b

Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study

J Neurol. 2026 Aug 17;273(9):526. doi: 10.1007/s00415-026-14039-x.ABSTRACTBACKGROUND: Oral anticoagulants (OACs), including vitamin K antagonists and direct OACs, reduce stroke risk in atrial fibrillation (AF), yet breakthrough ischemic stroke still occurs in 1-2% of patients annually despite adequa

Luteolin ameliorates sympathetic stress-induced myocardial injury by inhibiting the VEGFA/VEGFR2 and PI3K/Akt/NF-kappaB signaling pathways

Naunyn Schmiedebergs Arch Pharmacol. 2026 Aug 17. doi: 10.1007/s00210-026-05828-2. Online ahead of print.ABSTRACTSympathetic overactivation is a significant contributor to myocardial injury in cardiovascular disorders. Luteolin, a flavonoid, possesses anti-inflammatory, antioxidant, and anti-apoptot

Coronary calcium scoring in the evaluation of stable chest pain in general practice: a cluster-randomised trial

Heart. 2026 Aug 16:heartjnl-2025-327687. doi: 10.1136/heartjnl-2025-327687. Online ahead of print.ABSTRACTBACKGROUND: General practitioners (GPs) have limited tools for chest pain patients to identify (non-)obstructive coronary artery disease (OCAD). This trial evaluates whether GP access to the cor

Fetuses exposed to an episode of threatened preterm labor delivered at or near term show signs of cardiac remodeling

Ultrasound Obstet Gynecol. 2026 Aug 16. doi: 10.1002/uog.70304. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate whether fetuses exposed to threatened preterm labor (PTL) without intra-amniotic infection or inflammation (IAI), who were born ≥ 34 weeks' gestation, show signs of cardiac remodeling

Educational intervention to improve adherence after acute coronary syndrome

Medicina (B Aires). 2026;86(4):923-934.ABSTRACTINTRODUCTION: Patients discharged with a diagnosis of acute coronary syndrome (ACS) are at increased risk for recurrent cardiovascular events. Improved adherence to treatment has been associated with better outcomes. The objective of this study was to e

Estimating Eligibility for GLP-1 Receptor Agonists for Chronic Weight Management and Cardiovascular Disease in Australia: Cross-Sectional Analysis of National Health Survey Data

Med J Aust. 2026 Aug;224(8):e70253. doi: 10.5694/mja2.70253.ABSTRACTOBJECTIVE: To estimate population-level eligibility for glucagon-like peptide-1 receptor agonist (GLP-1RA) medications among adults in Australia, according to Therapeutic Goods Administration-approved indications for chronic weight

Predicting acute kidney injury in adults after cardiac surgery with a novel clinical metric: The cardiac diuretic-responsiveness index

JTCVS Open. 2026 Apr 20;32:101826. doi: 10.1016/j.xjon.2026.101826. eCollection 2026 Aug.ABSTRACTOBJECTIVE: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication after surgery, yet few risk models are used in practice. We evaluated whether a cardiac diuretic responsivenes

Patients with asymptomatic severe mitral regurgitation already have abnormal left ventricular myocardial sarcomeric ultrastructural characteristics

JTCVS Open. 2026 May 4;32:101821. doi: 10.1016/j.xjon.2026.101821. eCollection 2026 Aug.ABSTRACTOBJECTIVE: Mitral valve (MV) surgery remains a class I recommendation for patients with symptomatic severe primary mitral regurgitation (PMR). For asymptomatic patients with severe PMR and preserved left

Comparing hydrodynamic performance in full-root and graft-inclusion Ross technique: An ex vivo study

JTCVS Open. 2026 Jun 5;32:101917. doi: 10.1016/j.xjon.2026.101917. eCollection 2026 Aug.ABSTRACTOBJECTIVES: The Ross procedure is an attractive method for treating young patients with aortic valve disease, but the optimal surgical technique is still under discussion. This study aimed to evaluate the

Outcomes after lung retransplantation for restrictive allograft syndrome have not improved over 2 decades

JTCVS Open. 2026 May 15;32:101862. doi: 10.1016/j.xjon.2026.101862. eCollection 2026 Aug.ABSTRACTOBJECTIVE: In 2015, restrictive allograft syndrome (RAS) was first definitively associated with poorer outcomes after lung retransplantation compared with bronchiolitis obliterans syndrome (BOS). This st

Rheumatic Heart Disease in Pregnancy in Sub-Saharan Africa: A Case Series Emphasizing Gaps in Access to Definitive Care

Clin Med Insights Cardiol. 2026 Aug 14;20:11795468261479407. doi: 10.1177/11795468261479407. eCollection 2026.ABSTRACTRheumatic heart disease (RHD) remains a major cause of maternal cardiovascular morbidity and mortality in low-resource settings, particularly among women of reproductive age. Physiol

The weight of risk: epidemiological trends in mortality involving cardiac arrest and obesity in the United States (1999-2023)

J Diabetes Metab Disord. 2026 Aug 14;25(2):236. doi: 10.1007/s40200-026-02037-9. eCollection 2026 Dec.ABSTRACTBACKGROUND: Obesity is a major risk factor for cardiovascular disease, yet its role in cardiac arrest (CA) mortality remains a growing public health concern. This study analyzed disparities

Severe Tricuspid Regurgitation: Traumatic Papillary Muscle Rupture Mimicking Infective Endocarditis-A Case Report

Am J Case Rep. 2026 Aug 16;27:e952267. doi: 10.12659/AJCR.952267.ABSTRACTBACKGROUND Differentiating traumatic tricuspid regurgitation (TR) from infective endocarditis (IE) is clinically crucial in patients presenting with abnormal tricuspid valve findings after blunt chest trauma. Particularly, papi

Severity of periodontitis and risk of ischemic stroke: A systematic review and meta-analysis

J Periodontol. 2026 Aug 15. doi: 10.1002/jper.70185. Online ahead of print.ABSTRACTBACKGROUND: Periodontitis is a prevalent chronic inflammatory disease with a systemic inflammatory burden and is implicated with vascular pathology. This systematic review and meta-analysis evaluates the association b

Examining the Association Between Diabetes and Cardiovascular Outcomes in South Asian Compared with White North American Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction

Am J Cardiol. 2026 Aug 15:S0002-9149(26)00526-6. doi: 10.1016/j.amjcard.2026.08.015. Online ahead of print.ABSTRACTThe aim of this study was to examine the frequency and impact of diabetes (DM) in South Asian (SA) compared with white North American (WNA) patients with ST-elevation myocardial infarct

ASSESSING THE EFFECTIVENESS OF LIFESTYLE CLINIC INTERVENTIONS ON CARDIOMETABOLIC RISK FACTORS: A RETROSPECTIVE STUDY

Georgian Med News. 2026 Jun;(375):230-237.ABSTRACTBACKGROUND: Cardiometabolic disorders, including diabetes mellitus, hypertension, dyslipidemia, and obesity, represent a significant global health burden. While lifestyle interventions are recommended, evidence from real-world clinical settings in Sa

PREVENTION OF LOCAL POSTOPERATIVE COMPLICATIONS IN THE SURGICAL TREATMENT OF CHRONIC VENOUS INSUFFICIENCY OF THE LOWER EXTREMITIES (CEAP C3-C5)

Georgian Med News. 2026 Jun;(375):212-221.ABSTRACTINTRODUCTION: Chronic venous insufficiency of the lower extremities remains one of the most significant problems of modern vascular surgery and angiology because of its high prevalence, progressive course, and association with edema, trophic skin cha

Paroxysmal atrioventricular block as an initial presentation of bicuspid aortic valve calcification: a case report

Eur Heart J Case Rep. 2026 Aug 3;10(8):ytag582. doi: 10.1093/ehjcr/ytag582. eCollection 2026 Aug.ABSTRACTBACKGROUND: Atrioventricular (AV) conduction disturbances in bicuspid aortic valve (BAV) patients are typically attributed to age-related fibrosis or post-surgical trauma. Direct mechanical impin