Heart Fail Rev. 2026 Feb 3;31(1):23. doi: 10.1007/s10741-026-10595-6.ABSTRACTHyponatraemia remains the most prevalent electrolyte disturbance in heart failure, complicating clinical management and correlating with adverse outcomes. While traditionally viewed as a biomarker of disease severity, mount
Eur J Nutr. 2026 Feb 3;65(2):38. doi: 10.1007/s00394-026-03893-0.ABSTRACTPURPOSE: Cocoa is a significant source of theobromine, a bioactive compound proposed to provide cardiovascular protection. However, relatively few studies have provided conclusive evidence of the potential beneficial health eff
Food Funct. 2026 Feb 3. doi: 10.1039/d5fo04423e. Online ahead of print.ABSTRACTHyperuricemia (HUA) has become a worldwide metabolic disease, which can lead to acute gout attacks, renal dysfunction, uric acid (UA) urolithiasis, and cardiovascular damage. Probiotics, known for their cost-effectiveness
CONCLUSIONS: This study clarifies the role of the IK(Ca)-TRPC1-Ca^(2+) pathway in activating vascular Sca-1^(+) cells and establishes the contribution of the IK(Ca) channel to vascular restenosis development. Understanding how IK(Ca) channels affect the function of vascular Sca-1^(+) cells provides
Invest Ophthalmol Vis Sci. 2026 Feb 2;67(2):8. doi: 10.1167/iovs.67.2.8.ABSTRACTPURPOSE: Recent evidence suggests that simultaneous inhibition of multiple diabetes-induced molecular abnormalities is a valuable approach toward inhibiting the development of early stages of diabetic retinopathy (DR). T
J Am Heart Assoc. 2026 Feb 3:e045986. doi: 10.1161/JAHA.125.045986. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Intrinsic capacity (IC) represents a composite measure of physical and mental capacities. However, the
Clin Cardiol. 2026 Feb;49(2):e70267. doi: 10.1002/clc.70267.ABSTRACTINTRODUCTION: Atrial fibrillation (AF) is the most common and persistent type of arrhythmia that frequently co-exists with chronic ischemic heart disease (IHD), increasing the risk of adverse cardiovascular outcomes and mortality. W
Pacing Clin Electrophysiol. 2026 Feb 3. doi: 10.1111/pace.70149. Online ahead of print.ABSTRACTINTRODUCTION: Implantable cardioverter-defibrillators (ICDs) are the cornerstone of sudden cardiac death prevention in cardiomyopathies, but disease-specific structural and electrophysiological substrates
Vasc Med. 2026 Feb 3:1358863X251406525. doi: 10.1177/1358863X251406525. Online ahead of print.ABSTRACTMarfan syndrome (MFS) is a genetic disorder caused by mutations in the FBN1 gene, which encodes fibrillin-1, a crucial protein involved in the structure of elastic fibers and the regulation of trans
Pol Arch Intern Med. 2026 Feb 3:17219. doi: 10.20452/pamw.17219. Online ahead of print.ABSTRACTINTRODUCTION: Accurate cardiovascular disease (CVD) risk prediction is crucial for personalized preventive medicine.OBJECTIVES: To evaluate the effect of traditional risk factors on CVD mortality, and to
Circulation. 2026 Feb 3. doi: 10.1161/CIR.0000000000001416. Online ahead of print.ABSTRACTPremenopausal women presenting with acute coronary syndrome (ACS) are a unique and often underrecognized patient population. Although they are traditionally considered at lower cardiovascular risk than other gr
FASEB J. 2026 Feb 15;40(3):e71524. doi: 10.1096/fj.202502033RR.ABSTRACTPathological cardiac hypertrophy is a major contributor to heart failure and is often accompanied by ferroptosis and mitochondrial dysfunction. However, the upstream transcriptional mechanisms governing these processes remain poo
G Ital Cardiol (Rome). 2026 Feb;27(2):130-140. doi: 10.1714/4636.46470.ABSTRACTBACKGROUND: Although international guidelines recommend increasingly lower thresholds for low-density lipoprotein cholesterol (LDL-C), everyday clinical experience shows that many patients fail to reach these targets, exp
G Ital Cardiol (Rome). 2026 Feb;27(2):121-129. doi: 10.1714/4636.46469.ABSTRACTDespite the widespread use of lipid-lowering therapies, a significant proportion of patients with atherosclerotic cardiovascular disease fail to achieve the recommended LDL-cholesterol targets, thus remaining at high resi
J Cardiol Cases. 2025 Aug 5;32(5):199-203. doi: 10.1016/j.jccase.2025.07.001. eCollection 2025 Nov.ABSTRACTInfective endocarditis (IE) following transcatheter atrial septal defect (ASD) device closure is a rare but life-threatening complication. We report a case of a 41-year-old woman who developed
Am Heart J Plus. 2026 Jan 10;63:100719. doi: 10.1016/j.ahjo.2026.100719. eCollection 2026 Mar.ABSTRACTBACKGROUND: Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, arising from complex interactions among demographic, clinical, behavioral, and social determinants. Levera
Mol Ther Nucleic Acids. 2026 Jan 9;37(1):102830. doi: 10.1016/j.omtn.2026.102830. eCollection 2026 Mar 12.ABSTRACTMicroRNA-122-5p (miR-122) is primarily expressed in the liver and is increasingly released into the bloodstream during obesity. It impacts the function of non-liver tissues, such as vasc
Am J Prev Cardiol. 2026 Jan 19;26:101432. doi: 10.1016/j.ajpc.2026.101432. eCollection 2026 Apr.ABSTRACTINTRODUCTION: Cardiovascular-Kidney-Metabolic (CKM) syndrome provides a framework for early cardiometabolic and kidney dysfunction. While reproductive risk factors are associated with cardiovascul
Am J Prev Cardiol. 2026 Jan 12;26:101424. doi: 10.1016/j.ajpc.2026.101424. eCollection 2026 Apr.ABSTRACTBACKGROUND: Tools like Life's Simple 7 (LS7) can help estimate the risk of cardiovascular events in healthy subjects. Recently, the Life's Essential 8 (LE8) was developed, including sleep as an ad
Am J Prev Cardiol. 2026 Jan 19;26:101436. doi: 10.1016/j.ajpc.2026.101436. eCollection 2026 Apr.ABSTRACTBACKGROUND: Severe infections, particularly those requiring hospitalization, have been widely recognized as potential risk factors for cardiovascular and cerebrovascular diseases. However, the pre
The FXYD family (FXYD domain-containing ion transport regulators) proteins consist of short, single-pass transmembrane proteins that primarily regulate the Na^(+)/K^(+)-ATPase (NKA) pump, a key player in maintaining cellular ion homeostasis. Ranging from 60 to 160 amino acids in length, FXYD protein
JAAD Int. 2025 Dec 16;25:44-55. doi: 10.1016/j.jdin.2025.11.026. eCollection 2026 Apr.ABSTRACTBACKGROUND: Psoriasis increases atherosclerosis risk due to inflammation. To date, subclinical atherosclerosis (SA) in psoriasis has only been studied in individual vascular territories by imaging.OBJECTIVE
Alzheimers Dement. 2026 Feb;22(2):e71134. doi: 10.1002/alz.71134.ABSTRACTINTRODUCTION: Amyloid beta peptide (Aβ) accumulation in the brain is an Alzheimer´s disease (AD) hallmark. Sleep disturbances hamper Aβ production and clearance, thereby exacerbating the Aβ burden. The mechanisms involved remai
Innovations (Phila). 2026 Feb 3:15569845251401204. doi: 10.1177/15569845251401204. Online ahead of print.ABSTRACTOBJECTIVE: Esophageal cancer is a leading cause of cancer-related mortality, with a 5-year survival rate of 20%. Surgical resection remains the primary treatment for early and locally adv
