Impact of the invasively measured flow-gradient pattern on clinical outcomes and ventricular remodeling after transcatheter aortic valve implantation in patients with severe aortic stenosis and preserved ejection fraction

Clin Res Cardiol. 2026 Mar 30. doi: 10.1007/s00392-026-02881-y. Online ahead of print.ABSTRACTAIMS: To investigate clinical outcomes and cardiac remodeling according to cardiac magnetic resonance (CMR) of the invasively measured different flow/gradient entities of severe aortic stenosis (AS) with pr

Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation

N Engl J Med. 2026 Mar 28. doi: 10.1056/NEJMoa2517213. Online ahead of print.ABSTRACTBACKGROUND: For patients with atrial fibrillation, the use of oral anticoagulant therapy to prevent stroke is limited by the risk of bleeding. Left atrial appendage closure is considered for patients who are unsuita