Polygenic risk-based prediction of heart failure in young patients with atrial fibrillation
No abstractEuropace. 2025 Sep 1;27(9):euaf138. doi: 10.1093/europace/euaf138.NO ABSTRACTPMID:40910263 | DOI:10.1093/europace/euaf138
Closed atrium bipolar radiofrequency box lesion for concomitant surgical atrial fibrillation ablation
Front Cardiovasc Med. 2025 Aug 20;12:1655695. doi: 10.3389/fcvm.2025.1655695. eCollection 2025.ABSTRACTBACKGROUND: In patients with atrial fibrillation (AF) undergoing coronary artery bypass grafting (CABG) or aortic valve replacement (AVR), many surgeons are reluctant to open the left atrium for su
Strategies for population-level identification of post-acute sequelae of COVID-19 through health administrative data
Front Public Health. 2025 Aug 20;13:1637112. doi: 10.3389/fpubh.2025.1637112. eCollection 2025.ABSTRACTINTRODUCTION: Post-acute sequelae of COVID-19 (PASC) encompass several clinical outcomes, from new-onset symptoms to both acute and chronic diagnoses, including pulmonary and extrapulmonary manifes
Association of sedentary behavior with atrial fibrillation-related biomarkers in a population with overweight or obesity
medRxiv [Preprint]. 2025 Aug 28:2025.08.25.25334401. doi: 10.1101/2025.08.25.25334401.ABSTRACTBACKGROUND: Blood biomarkers can characterize the atrial substrate, helping to elucidate mechanisms of atrial fibrillation (AF) development. Understanding whether sedentary behavior affects AF-related bioma
Transcriptional Readthrough at Atf4 Locus Suppresses Rps19bp1 and Impairs Heart Development
CONCLUSIONS: We found that the downregulation of Rps19bp1 , not loss of ATF4 function, underlying the cardiac phenotypes in Atf4 ^(cKO(e2/3/pA)) mice. The reduced expression of Rps19bp1 in Atf4 ^(cKO(e2/3/pA)) mice is likely due to the unintentional deletion of Atf4 polyA signal and subsequent trans
A Novel Technique for Conduction System Pacing in Patients Undergoing Simultaneous Ablation of the Atrioventricular Node Using Axillary Venous Access
J Innov Card Rhythm Manag. 2025 Aug 15;16(8):6407-6411. doi: 10.19102/icrm.2025.16083. eCollection 2025 Aug.ABSTRACTConduction system pacing has emerged as a new pacing technique to achieve cardiac physiologic pacing, but its utility and safety in patients with atrial fibrillation undergoing simulta
Outcomes and Safety of Catheter Ablation in the Elderly
J Innov Card Rhythm Manag. 2025 Aug 15;16(8):6412-6419. doi: 10.19102/icrm.2025.16084. eCollection 2025 Aug.ABSTRACTCatheter ablation has emerged as a first-line therapy for many arrhythmias. However, data on the safety and outcomes of catheter ablation in the elderly population remain limited. Here
Quantitative histopathologic profiling of arterial dissection-related thrombi in acute ischemic stroke: etiological comparisons
Front Neurol. 2025 Aug 20;16:1640562. doi: 10.3389/fneur.2025.1640562. eCollection 2025.ABSTRACTINTRODUCTION: Arterial dissection is an important etiology of stroke in young adults and may demonstrate distinct thrombus characteristics. While most studies have focused on compositional differences bet
Patient Comfort and Response Pattern Following Pulsed-Field Ablation Compared to Radiofrequency Ablation for Atrial Fibrillation
J Cardiovasc Electrophysiol. 2025 Sep 4. doi: 10.1111/jce.70077. Online ahead of print.ABSTRACTBACKGROUND: Pulsed-field ablation (PFA) for atrial fibrillation (AF) offers several advantages compared to thermal ablation, however direct comparisons of patient-reported outcomes after PFA and radiofrequ
Chronotropic incompetence during exercise or pharmacological stress is associated with reduced survival in patients with chronic coronary syndromes
Eur J Prev Cardiol. 2025 Sep 5:zwaf492. doi: 10.1093/eurjpc/zwaf492. Online ahead of print.ABSTRACTAIMS: Chronotropic incompetence (CI) is a biomarker of cardiac autonomic dysfunction. The aim of the study is to assess the risk stratification value of CI during exercise or pharmacological stress ech
Obesity and Atrial Fibrillation: From Mechanisms to Treatment
Heart Lung Circ. 2025 Sep 3:S1443-9506(25)01574-4. doi: 10.1016/j.hlc.2025.08.003. Online ahead of print.ABSTRACTBy 2050, it is projected that 3.8 billion people worldwide will be overweight or obese. Alongside this growing burden of obesity is a parallel rise in the incidence and prevalence of atri
From Cushion to Culprit: The Role of Epicardial Adipose Tissue in Cardiovascular Disease
Heart Lung Circ. 2025 Sep 3:S1443-9506(25)01558-6. doi: 10.1016/j.hlc.2025.07.010. Online ahead of print.ABSTRACTEpicardial adipose tissue (EAT) is the layer of fat located between the visceral pericardium and the myocardium. Emerging research has signified its role in the development of various car
The Persisting Burden of Rheumatic Heart Disease: Insights From the Ina-RHD Study
No abstractJACC Asia. 2025 Sep;5(9):1184-1186. doi: 10.1016/j.jacasi.2025.06.007.NO ABSTRACTPMID:40908090 | DOI:10.1016/j.jacasi.2025.06.007
Reply to letters to the editor part 1: Duration of atrial fibrillation and cardiac biomarkers: Data from the RACE II study
No abstractInt J Cardiol. 2025 Sep 2:133849. doi: 10.1016/j.ijcard.2025.133849. Online ahead of print.NO ABSTRACTPMID:40907828 | DOI:10.1016/j.ijcard.2025.133849
Comparative effectiveness of sodium-glucose cotransporter 2 inhibitors along with colchicine versus colchicine alone among coronary artery disease and type 2 diabetes patients
Prog Cardiovasc Dis. 2025 Sep 2:S0033-0620(25)00132-X. doi: 10.1016/j.pcad.2025.08.010. Online ahead of print.ABSTRACTBACKGROUND: Colchicine, an anti-inflammatory agent, has been demonstrated to reduce adverse cardiovascular events in coronary artery disease (CAD) patients. Sodium-Glucose Cotranspor
Extra-Virgin Olive Oil and Additional Cardiovascular Outcomes in the PREDIMED Trial: An Outcome-Wide Perspective
Am Heart J. 2025 Sep 2:S0002-8703(25)00321-7. doi: 10.1016/j.ahj.2025.08.021. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Olive oil, increasingly consumed in the U.S., has been inversely associated with cardiovascular disease (CVD) risk. However, previous studies did not assess a broad spectr
Acalabrutinib treatment for older (≥80 years old) and/or frail patients with CLL: primary end point analysis of the CLL-Frail trial
Blood. 2025 Sep 4:blood.2025028550. doi: 10.1182/blood.2025028550. Online ahead of print.ABSTRACTBecause frail and patients ≥80 years with CLL are still underrepresented in clinical trials, the CLL-Frail trial aimed to evaluate the efficacy and safety of acalabrutinib in these patients. The primary
Transgenic mice overexpressing Pitx2 in the atria develop tachycardia-bradycardia syndrome
PLoS One. 2025 Sep 4;20(9):e0330397. doi: 10.1371/journal.pone.0330397. eCollection 2025.ABSTRACTSinoatrial node (SAN) dysfunction often accompanies supraventricular tachyarrhythmias such as atrial fibrillation (AF), which is referred to as tachycardia-bradycardia syndrome (TBS). Although there have
Endovascular thrombectomy in young patients with acute vertebrobasilar artery occlusion
Neurol Res. 2025 Sep 4:1-10. doi: 10.1080/01616412.2025.2549034. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Data on endovascular thrombectomy (EVT) for acute vertebrobasilar artery occlusion (VBAO) in young adults are limited. We compared clinical characteristics and outcomes after EVT be
Role of Morbidity Clusters in Midlife on Ischemic Stroke Incidence and Severity: The ARIC Study
Stroke. 2025 Sep 4. doi: 10.1161/STROKEAHA.124.049496. Online ahead of print.ABSTRACTBACKGROUND: There is a strong association between vascular risk factors, particularly in midlife, and stroke risk; therefore, the co-occurrence of multiple risk factors may be especially informative. This study used
Thinking Outside the Box: Case Report of a Rare Quadricuspid Aortic Valve as an Underrecognized Cause of Heart Failure and Atrial Fibrillation
J Med Cases. 2025 Aug 7;16(8):277-281. doi: 10.14740/jmc5153. eCollection 2025 Aug.ABSTRACTQuadricuspid aortic valve (QAV) is a rare congenital anomaly with an estimated incidence of 0.008% to 0.043% based on autopsy and echocardiographic studies. Although often asymptomatic, it can lead to progress
The Causal Mechanism Between the Dipeptidyl Peptidase-4, Heart Failure, and Other Cardiovascular Diseases: A Mendelian Randomization and Mediation Study
Int J Endocrinol. 2025 Aug 26;2025:2357272. doi: 10.1155/ije/2357272. eCollection 2025.ABSTRACTAims: Dipeptidyl peptidase-4 (DPP4) inhibitors are commonly used to treat type 2 diabetes. However, the causality of it on cardiovascular diseases (CVDs) is controversial. This study aimed (1) to investiga
Effect of Stellate Ganglion Block on Preventing Atrial Fibrillation After Esophagectomy: A Double-Blind Randomized Controlled Trial
Drug Des Devel Ther. 2025 Aug 29;19:7481-7492. doi: 10.2147/DDDT.S538004. eCollection 2025.ABSTRACTBACKGROUND: Postoperative atrial fibrillation (POAF) is a common complication after esophagectomy and is associated with adverse outcomes. This study investigated whether preoperative stellate ganglion
Advances in catheter ablation for patients with atrial fibrillation and heart failure
Zhonghua Nei Ke Za Zhi. 2025 Sep 1;64(9):886-890. doi: 10.3760/cma.j.cn112138-20250318-00163.ABSTRACT心房颤动（房颤）是常见的心律失常，常与心力衰竭（心衰）共同存在并相互影响，严重影响患者生活质量，并显著增加患者卒中、认知功能下降、心衰再住院以及全因死亡风险。多项临床研究显示了房颤导管消融在改善左心室射血分数、心衰再住院率和病死率等方面的优势。本文就房颤导管消融在不同表型心衰患者中的最新研究证据和当前我们所面临的问题作进一步讨论。.PMID:40904300 | DOI:10.3760/cma.